Atenolol (Zenobloc 50) 50mg Film Coated Beta Blocking Agent Tablet 100's

Atenolol (Zenobloc 50) 50mg Film-Coated Beta Blocking Agent Tablet 100's

Product Description:

Zenobloc 50 contains Atenolol, a beta-blocker that is commonly prescribed to treat a range of cardiovascular conditions. It is a 50mg film-coated tablet available in a bottle of 100 tablets. Atenolol works by blocking the action of certain chemicals, such as adrenaline, on the heart and blood vessels. This helps reduce the heart rate, blood pressure, and strain on the heart, making it an effective treatment for hypertension (high blood pressure) and other heart-related conditions.

Indications:

Zenobloc 50 (Atenolol) is indicated for the following conditions:

1. Hypertension (High Blood Pressure):

   • Used to lower blood pressure, reducing the risk of strokes, heart attacks, and kidney problems.

2. Angina Pectoris (Chest Pain):

   • Helps to relieve chest pain associated with angina by reducing the heart’s oxygen demand.

3. Acute Myocardial Infarction (Heart Attack):

   • Used to reduce the risk of further heart attacks and improve survival after a heart attack.

4. Arrhythmias (Irregular Heartbeats):

   • Effective in treating abnormal heart rhythms, such as atrial fibrillation and ventricular arrhythmias.

5. Prevention of Migraines:

   • Atenolol is sometimes used off-label to help prevent migraines.

6. Anxiety (Off-Label):

   • Can be used for reducing the physical symptoms of anxiety, such as rapid heart rate and shaking.

Dosage and Administration:

For Hypertension:

• Initial dose: 50 mg once daily.

• Maintenance dose: 50 mg to 100 mg once daily, depending on response.

• Maximum dose: 100 mg once daily.

For Angina:

• Starting dose: 50 mg once daily.

• Maintenance dose: 50 mg to 100 mg once daily, based on effectiveness and tolerability.

For Post-Myocardial Infarction (Heart Attack):

• Starting dose: 50 mg once daily.

• Maintenance dose: May increase to 100 mg once daily, depending on clinical response.

For Arrhythmias:

• Dosage should be individualized by the healthcare provider based on the type and severity of the arrhythmia.

For Migraine Prevention (Off-label use):

• Typical dose: 25 mg to 50 mg once daily, adjusted according to patient response.

Administration:

• Oral use: Take the tablet with a glass of water, preferably at the same time each day.

• It can be taken with or without food.

Side Effects:

While Zenobloc 50 (Atenolol) is generally well-tolerated, it may cause side effects in some individuals. Common and rare side effects include:

Common Side Effects:

• Fatigue or tiredness.

• Dizziness or lightheadedness.

• Cold hands or feet.

• Bradycardia (slow heart rate).

• Low blood pressure (hypotension).

Serious Side Effects (Rare):

• Shortness of breath (due to worsening of pre-existing heart failure).

• Worsening of asthma or bronchospasm.

• Severe allergic reactions (e.g., rash, itching, swelling of the face, lips, or throat).

• Depression or mood changes.

• Heart failure symptoms such as fluid retention, swelling, or sudden weight gain.

• Hypoglycemia (low blood sugar), especially in diabetic patients.

Contraindications:

Zenobloc 50 (Atenolol) is contraindicated in the following conditions:

1. Severe Bradycardia (extremely slow heart rate).

2. Heart Block (2nd or 3rd degree), unless a pacemaker is in place.

3. Severe Hypotension (low blood pressure).

4. Uncontrolled Heart Failure (especially in acute decompensated heart failure).

5. Asthma or Chronic Obstructive Pulmonary Disease (COPD) with bronchospasm (in some patients).

6. Allergy to Atenolol or other beta-blockers.

7. Pregnancy (especially in the first trimester) and Breastfeeding (unless deemed essential by a healthcare provider).

8. Pheochromocytoma (a rare tumor of the adrenal gland that can cause high blood pressure), unless alpha-blocker therapy is also being used.

Precautions:

1. Diabetes:

   • Atenolol can mask the symptoms of low blood sugar (hypoglycemia), such as a rapid heart rate, especially in diabetic patients.

2. Thyroid Disease:

   • Use with caution in patients with thyroid disorders as beta-blockers may mask the symptoms of hyperthyroidism.

3. Kidney Disease:

   • Atenolol is primarily excreted by the kidneys, so it should be used with caution in patients with impaired renal function.

4. Liver Disease:

   • Although Atenolol is minimally metabolized in the liver, caution should be exercised when prescribing it to individuals with liver impairment.

5. Gradual Withdrawal:

   • Atenolol should not be abruptly discontinued, especially in patients with heart disease, as this may lead to an increased risk of heart attack or other cardiac events. The dosage should be gradually reduced under a doctor's supervision.

Drug Interactions:

• Calcium Channel Blockers (e.g., Verapamil, Diltiazem): Combining with Atenolol can increase the risk of bradycardia and heart block.

• Antiarrhythmic Drugs (e.g., Amiodarone, Quinidine): Can increase the risk of arrhythmias.

• Insulin and Oral Hypoglycemic Agents: Atenolol may mask the symptoms of hypoglycemia.

• NSAIDs (Nonsteroidal Anti-inflammatory Drugs): Can reduce the effectiveness of Atenolol in treating high blood pressure.

• Clonidine: Withdrawal of Clonidine after co-administration with Atenolol can cause a severe increase in blood pressure.

Overdose:

In the case of overdose, symptoms may include:

• Severe bradycardia (very slow heart rate).

• Hypotension (low blood pressure).

• Cardiac arrest.

• Bronchospasm.

• Hypoglycemia.

Management of Overdose:

• Immediate medical attention is required.

• Treatment includes supportive care, administration of atropine for bradycardia, and the use of a vasopressor to support blood pressure.

Conclusion:

Zenobloc 50 (Atenolol) is an effective medication for managing conditions like hypertension, angina, arrhythmias, and post-heart attack care. By reducing the heart rate and lowering blood pressure, it helps reduce the workload on the heart and improve cardiovascular health. As with any medication, it's important to follow the prescribed dosage and consult with a healthcare provider if you have any existing medical conditions or are taking other medications.