Cefixime (Sanix 200) 200mg Film Coated Tablet 30's

00mg Film Coated

ANTIBACTERIAL (CEPHALOSPORIN)

Certainly! Here is the detailed information for Cefixime (Sanix 200) 200mg Film-Coated Tablet 30's:

Product Description:

Sanix 200 (Cefixime 200mg) is an antibiotic in the cephalosporin class. Each tablet contains 200mg of Cefixime, an active ingredient that works by inhibiting bacterial cell wall synthesis, leading to the death of bacteria. It is effective against a broad spectrum of gram-positive and gram-negative bacteria. Cefixime is commonly used to treat various bacterial infections.

• Sanix 200 comes in film-coated tablets, and each bottle contains 30 tablets.

• It is used primarily for the oral treatment of bacterial infections and is known for its convenient once-daily dosing, which enhances patient compliance.

Indications:

Sanix 200 (Cefixime 200mg) is indicated for the treatment of the following bacterial infections:

1. Upper Respiratory Tract Infections:

   • Pharyngitis (sore throat)

   • Tonsillitis (inflammation of the tonsils)

   • Sinusitis (sinus infection)

   • Otitis media (middle ear infection)

2. Lower Respiratory Tract Infections:

   • Bronchitis (inflammation of the bronchi)

   • Pneumonia (lung infection)

3. Urinary Tract Infections (UTIs):

   • Cystitis (bladder infection)

   • Pyelonephritis (kidney infection)

4. Gonorrhea: Cefixime is used for the treatment of uncomplicated gonorrhea, particularly in cases where penicillin-resistant strains are suspected.

5. Other Infections: It may also be used for infections of the skin, soft tissues, and biliary tract (gallbladder).

Dosage:

Sanix 200 (Cefixime 200mg) tablets should be taken orally, with or without food. The dosage depends on the type and severity of the infection, as well as the patient’s age and renal function.

For Adults and Children Over 12 Years:

• The usual dose is 200mg once daily. In some cases, the dose can be increased to 400mg once daily for more severe infections.

For Children (6 months to 12 years):

• The typical pediatric dose is 8mg/kg/day, divided into two doses (every 12 hours) or given as a single dose. The dosage should not exceed 400mg/day.

For Renal Impairment:

• In patients with severe renal impairment, dose adjustments may be necessary. It is recommended to monitor renal function and adjust the dose as needed.

Side Effects:

Although Cefixime (Sanix 200) is generally well-tolerated, it can cause side effects in some individuals. Below are common and serious side effects associated with this medication:

Common Side Effects:

• Diarrhea: A frequent side effect of many antibiotics, including Cefixime.

• Nausea and vomiting: Mild gastrointestinal upset may occur.

• Abdominal pain or discomfort: Stomach cramps or bloating.

• Headache: May be experienced by some patients.

• Dizziness: Can occur, especially with prolonged use.

• Fatigue: General tiredness or weakness.

Serious Side Effects (Less Common):

• Allergic reactions: Rash, itching, swelling, or difficulty breathing. These may indicate an allergic reaction.

• Clostridium difficile-associated diarrhea (C. difficile): Prolonged use of antibiotics can lead to overgrowth of harmful bacteria in the intestines, causing severe diarrhea.

• Liver issues: Liver enzymes may be elevated, indicating liver dysfunction.

• Severe abdominal pain: May indicate an issue with the gastrointestinal tract, like pseudomembranous colitis.

• Blood dyscrasias: Rare, but could include anemia, leukopenia, or thrombocytopenia (reduced red blood cells, white blood cells, or platelets).

If any of the above serious side effects occur, you should immediately discontinue the medication and consult a healthcare provider.

Contraindications:

Sanix 200 (Cefixime 200mg) is contraindicated in the following situations:

1. Hypersensitivity to Cefixime or any other cephalosporins. If you have a known allergy to Cefixime or similar antibiotics (e.g., penicillin), this medication should not be used.

2. History of severe allergic reactions: Patients who have previously had anaphylactic reactions to beta-lactam antibiotics (such as penicillins or cephalosporins) should avoid using Cefixime.

3. Severe Renal Impairment: In patients with severe renal dysfunction (e.g., glomerular filtration rate (GFR) less than 30 mL/min), the drug should be used with caution, and the dosage may need to be adjusted.

4. Neonates and Infants Under 6 Months: Cefixime is not recommended for children under 6 months old due to potential safety concerns and lack of established dosage guidelines in this age group.

Precautions:

• Pregnancy and Lactation: While Cefixime is generally considered safe for use during pregnancy (Category B), it should only be used when the benefits outweigh the risks. It is excreted in breast milk, so it should be used cautiously while breastfeeding.

• Renal Impairment: Patients with renal impairment should have their dosage adjusted based on renal function, as the drug is primarily excreted by the kidneys.

• Gastrointestinal Conditions: If you have a history of gastrointestinal issues like inflammatory bowel disease or colitis, use Cefixime with caution.

• Superinfection: Prolonged or inappropriate use of antibiotics like Cefixime may result in the overgrowth of non-susceptible organisms, such as fungi or Clostridium difficile. In such cases, appropriate treatment should be started.

• Disruption of Flora: Like all antibiotics, Cefixime can disrupt the normal bacterial flora, leading to yeast infections (like thrush or vaginal candidiasis).

Drug Interactions:

• Probenecid: This medication can increase the levels of Cefixime in the blood, so concurrent use may require dose adjustments.

• Antacids and H2 blockers: These may reduce the absorption of Cefixime if taken simultaneously. It’s best to space out the timing of these medications.

• Other antibiotics: Combining Cefixime with other antibiotics (e.g., aminoglycosides or diuretics) could increase the risk of kidney toxicity.

Summary:

Sanix 200 (Cefixime 200mg) is a broad-spectrum cephalosporin antibiotic used to treat a wide range of bacterial infections, including respiratory tract infections, urinary tract infections, gonorrhea, and skin infections. It works by inhibiting bacterial cell wall synthesis, thus killing bacteria.

• The usual adult dose is 200mg once daily, though it can be increased to 400mg for more severe infections. Side effects may include diarrhea, nausea, headache, and dizziness. Serious side effects include allergic reactions and Clostridium difficile infection.

• Sanix 200 should not be used in individuals with a history of severe allergies to cephalosporins or severe renal impairment.

• Precautions should be taken for pregnant or breastfeeding women, those with renal or gastrointestinal conditions, and those using it for prolonged periods.

As always, it is important to follow the prescribed dosage and consult a healthcare provider for any concerns, especially regarding side effects or the need for dose adjustments.