Cefixime ( Supraphil) 200mg Tablet 30's

Antibacterial
(Cephalosporin)

Certainly! Here's a detailed breakdown for Cefixime (Supraphil) 200mg Tablet 30's:

Product Description:

Cefixime (Supraphil) 200mg Tablets contain Cefixime, a broad-spectrum antibiotic belonging to the cephalosporin class. It works by inhibiting the growth of bacteria, making it effective in treating various bacterial infections. Cefixime is used to treat infections caused by susceptible bacteria, including those in the respiratory tract, urinary tract, and other parts of the body.

Each tablet contains 200 mg of Cefixime, and the pack contains 30 tablets.

Indications:

Cefixime (Supraphil) is indicated for the treatment of infections caused by susceptible bacteria. These include:

1. Respiratory Tract Infections:

   • Acute bronchitis

   • Chronic bronchitis

   • Pneumonia

   • Tonsillitis and pharyngitis

   • Sinusitis

2. Urinary Tract Infections (UTIs):

   • Cystitis (bladder infection)

   • Pyelonephritis (kidney infection)

3. Sexually Transmitted Infections (STIs):

   • Gonorrhea (uncomplicated)

4. Ear Infections:

   • Otitis media (middle ear infection)

5. Other Bacterial Infections:

   • Skin and soft tissue infections caused by susceptible organisms.

Note: Cefixime is effective against many Gram-positive and Gram-negative bacteria, but it is important to perform appropriate testing to confirm the presence of susceptible bacteria before treatment.

Dosages:

The usual dose of Cefixime (Supraphil) will vary based on the type of infection being treated and the patient's age and condition. Below are general dosing recommendations:

For Adults:

• Uncomplicated Urinary Tract Infections (UTI):

  • 200 mg once daily for 7-14 days, depending on the severity of the infection.

• Respiratory Tract Infections (like pneumonia or bronchitis):

  • 200 mg once daily or 100 mg every 12 hours for 7-14 days, based on the infection's severity and type.

• Gonorrhea:

  • 400 mg as a single dose.

For Children:

• Children aged 6 months to 12 years:

  • The typical dose is 8 mg/kg once daily or divided into two doses every 12 hours, up to a maximum of 400 mg/day.

• Children under 6 months:

  • Cefixime is not generally recommended for children under 6 months of age due to limited safety data.

Note: Cefixime should be taken with food to reduce gastrointestinal discomfort, though it can also be taken without food.

Side Effects:

Like all medications, Cefixime (Supraphil) can cause side effects, though not everyone will experience them. Common and serious side effects may include:

Common Side Effects:

• Gastrointestinal symptoms:

  • Diarrhea

  • Nausea

  • Vomiting

  • Abdominal pain

  • Indigestion

• Headache

• Dizziness

• Rash

Serious Side Effects:

• Severe allergic reactions (anaphylaxis), including:

  • Swelling of the face, lips, tongue, or throat

  • Difficulty breathing

  • Hives

• Clostridium difficile-associated diarrhea (CDAD):

  • A potentially serious form of diarrhea caused by an overgrowth of Clostridium difficile bacteria.

• Liver problems:

  • Signs include yellowing of the skin or eyes (jaundice), dark urine, and upper right abdominal pain.

• Blood disorders:

  • Thrombocytopenia (low platelet count) or leukopenia (low white blood cell count), leading to symptoms such as unusual bruising, fatigue, or infections.

• Severe skin reactions:

  • Stevens-Johnson Syndrome or toxic epidermal necrolysis, though these are rare.

If you experience any of these serious side effects, stop taking the medication and seek medical attention immediately.

Contraindications:

Cefixime (Supraphil) should not be used in the following situations:

1. Hypersensitivity (allergy) to Cefixime, cephalosporins, or any of the other components in the formulation.

   • If you have had a severe allergic reaction to penicillin or other beta-lactam antibiotics, you may be at increased risk of an allergic reaction to Cefixime.

2. History of severe gastrointestinal reactions:

   • If you have a history of severe colitis (inflammation of the colon) related to antibiotic use, such as Clostridium difficile-associated diarrhea, you should use Cefixime with caution.

3. Renal (kidney) impairment:

   • Cefixime should be used with caution in patients with severe kidney disease, as the drug is eliminated by the kidneys. The dosage may need to be adjusted based on kidney function.

4. Pregnancy:

   • Cefixime is classified as a Category B drug during pregnancy (based on animal studies). It has been shown to be safe in animal studies, but should still only be used during pregnancy if clearly needed and under the supervision of a healthcare provider.

5. Breastfeeding:

   • Cefixime is excreted in breast milk in small amounts. It is generally considered safe for use during breastfeeding, but consult your healthcare provider before using Cefixime while nursing.

Precautions:

• Diarrhea: If you develop persistent or severe diarrhea while taking Cefixime, you should contact your doctor as this could be a sign of Clostridium difficile infection (CDAD), which requires prompt treatment.

• Renal function: In patients with mild to moderate renal impairment, the dose of Cefixime may need to be reduced. Monitoring kidney function is important during treatment.

• Superinfection: As with all antibiotics, prolonged use of Cefixime can result in superinfection due to the overgrowth of non-susceptible organisms, including fungi.

• Blood tests: If you are receiving prolonged treatment, your doctor may monitor blood tests, as Cefixime can cause changes in blood cell counts.

Important Notes:

• Completion of the course: It is essential to complete the entire prescribed course of Cefixime to ensure that the infection is fully treated and to reduce the risk of antibiotic resistance.

• Missed dose: If you miss a dose of Cefixime, take it as soon as you remember, unless it is almost time for your next dose. Do not take two doses at once to make up for a missed dose.

Conclusion:

Cefixime (Supraphil) 200mg Tablets is a broad-spectrum antibiotic used to treat a variety of bacterial infections, including those in the respiratory and urinary tracts, as well as ear and skin infections. It works by inhibiting bacterial growth and is generally well-tolerated, although it may cause side effects such as gastrointestinal issues or allergic reactions in some individuals. Always take Cefixime as directed by your healthcare provider and complete the full course to ensure effective treatment and reduce the risk of resistance. If you experience any severe side effects or signs of an allergic reaction, seek medical attention immediately.