Cetirizine Hydrochloride (Medrizine) 5mg/5ml Syrup 60ml

5mg/5ml Syrup

ANTIHISTAMINE

Here is the detailed information for Cetirizine Hydrochloride (Medrizine) 5mg/5ml Syrup 60ml:

Product Description:

Cetirizine Hydrochloride (Medrizine) is an antihistamine that is commonly used to relieve allergy symptoms such as runny nose, sneezing, itching, and watery eyes. It works by blocking histamine, a substance produced by the body during an allergic reaction. Medrizine Syrup is formulated with 5mg of Cetirizine per 5ml of syrup, making it an effective treatment for both adults and children. The syrup has a pleasant taste and is designed for easy dosing, especially for individuals who may have difficulty swallowing tablets or tablets.

Cetirizine is a second-generation antihistamine, which means it typically causes less sedation compared to first-generation antihistamines.

Indications:

Cetirizine Hydrochloride (Medrizine) Syrup is indicated for the treatment of:

1. Allergic Rhinitis:

   • For seasonal and perennial allergies (such as hay fever), where symptoms include sneezing, itchy nose, runny nose, and watery eyes.

2. Allergic Conjunctivitis:

   • For itchy, red, watery eyes caused by allergic reactions.

3. Urticaria (Hives):

   • For the treatment of hives (raised, red, itchy skin rashes), often associated with allergies.

4. Insect Bites:

   • Relief of itching caused by insect stings or bites.

5. Other Allergic Reactions:

   • Hay fever, pet dander, or reactions to dust mites.

Dosage and Administration:

Cetirizine Hydrochloride (Medrizine) Syrup is typically taken once daily. Dosing depends on the age of the patient. The syrup should be measured using a proper measuring spoon or oral syringe for accurate dosing.

For Children:

• 2 to 6 years: 2.5 ml (2.5 mg) once daily.

• 6 to 12 years: 5 ml (5 mg) once daily, or 2.5 ml (2.5 mg) twice daily.

For Adults and Children Over 12 years:

• 5 ml (5 mg) once daily, or in some cases, 10 ml (10 mg) once daily depending on the severity of symptoms.

Note: If the child has renal (kidney) impairment, the dosage may need to be adjusted by a healthcare provider.

Side Effects:

Most people tolerate Cetirizine Hydrochloride (Medrizine) well, but some may experience side effects. Common and serious side effects are listed below:

Common Side Effects:

• Drowsiness (although less than first-generation antihistamines, some people may still experience mild sedation).

• Dry mouth.

• Headache.

• Stomach upset or nausea.

• Fatigue or tiredness.

• Dizziness.

Less Common Side Effects:

• Sleep disturbances such as difficulty falling asleep.

• Skin rash or itching.

• Sore throat or cold symptoms.

Serious Side Effects (Seek medical attention immediately if you experience):

• Severe allergic reactions (e.g., swelling of the face, lips, or throat, difficulty breathing, severe dizziness).

• Fast or irregular heartbeat.

• Severe drowsiness, confusion, or hallucinations.

• Liver problems: symptoms like yellowing of the skin or eyes (jaundice), dark urine, or persistent abdominal pain.

Overdose Symptoms:

• If more than the recommended dose is taken, symptoms of overdose may include drowsiness, nausea, and fatigue. Immediate medical attention is required in case of overdose.

Contraindications:

Cetirizine Hydrochloride (Medrizine) should not be used in the following situations:

1. Hypersensitivity to Cetirizine or Other Antihistamines:

   • If the patient is allergic to Cetirizine, hydroxyzine, or any of the ingredients in the syrup, it should not be used.

2. Severe Renal Impairment:

   • Cetirizine should be used with caution or avoided in patients with severe kidney disease (renal insufficiency) as the drug is primarily eliminated through the kidneys. Dosing adjustments are necessary for such patients.

3. Liver Disease:

   • Caution is required in patients with liver disease or liver impairment because the liver processes the medication. If there is significant liver impairment, a doctor may need to adjust the dosage.

4. Pregnancy and Breastfeeding:

   • Pregnancy: Cetirizine should be used during pregnancy only if clearly needed and prescribed by a healthcare provider. It is classified as a Category B medication, meaning there is no evidence of harm to the fetus in animal studies, but should still be used cautiously.

   • Breastfeeding: Cetirizine passes into breast milk in small amounts, but it is generally considered safe for use during breastfeeding at standard doses. However, it’s always best to consult with a doctor before use.

Precautions:

1. Sedation:

   • Although Cetirizine is considered a non-sedating antihistamine, it can cause drowsiness in some individuals. Caution should be exercised when engaging in activities requiring alertness (e.g., driving, operating machinery).

2. Kidney or Liver Disease:

   • Individuals with renal or liver impairments may need dose adjustments. It's important to consult a doctor to determine the right dose for these patients.

3. Elderly Patients:

   • In elderly patients, drowsiness may be more pronounced, and renal or liver function may be impaired, requiring dose adjustments.

4. Alcohol:

   • It is advisable to avoid consuming alcohol while using Cetirizine as it may enhance drowsiness or cause an exaggerated sedative effect.

5. Over-the-counter use:

   • Cetirizine is available over-the-counter, but if symptoms persist for more than a few days or worsen, medical consultation should be sought.

Summary:

Cetirizine Hydrochloride (Medrizine) 5mg/5ml Syrup is an antihistamine used to treat a variety of allergy symptoms, including hay fever, allergic conjunctivitis, and urticaria (hives). It works by blocking the action of histamine in the body, which is responsible for causing allergy symptoms. The syrup is easy to administer, especially for children, and is effective in relieving symptoms like sneezing, itching, and watery eyes.

• Indications: Allergic rhinitis, allergic conjunctivitis, urticaria, insect bites, and other allergic reactions.

• Dosage: Based on age, with typical doses for children 2-6 years at 2.5 ml and for adults at 5 ml once daily.

• Side Effects: Common effects include drowsiness, headache, dry mouth, and fatigue. Serious side effects can include severe allergic reactions or liver issues.

• Contraindications: Avoid use in individuals with allergy to cetirizine, severe renal impairment, or severe liver disease.

Cetirizine Hydrochloride (Medrizine) is an effective and generally safe antihistamine for managing allergy symptoms, but it should be used according to the prescribed dosage to avoid potential side effects. Always consult a healthcare provider if there are any concerns, especially for individuals with liver or kidney conditions.