Cinnarizine (Cinnarex) 25mg Tablets 100's

Description:
Cinnarizine is an antihistamine that stops you feeling or being sick (nausea or vomiting). It works by blocking the effects of histamine in your brain to reduce the symptoms of travel sickness (motion sickness). It also helps to improve blood flow in the inner ear.

Product Description:

Cinnarizine (Cinnarex) 25mg Tablets are an antihistamine used primarily for motion sickness and vertigo. It is a first-generation antihistamine, which means it can cause drowsiness as it blocks the effects of histamine, a chemical that contributes to allergic reactions, nausea, and balance issues. Cinnarizine is often used to alleviate symptoms related to nausea, dizziness, vomiting, and motion sickness.

The product comes in 25mg tablet form, and the pack contains 100 tablets, designed for oral administration.

Key Features:

• Active Ingredient: Cinnarizine 25mg per tablet.

• Formulation: Oral tablets for easy administration.

• Indications: Used to treat motion sickness, vertigo, and symptoms of inner ear problems that affect balance.

• Drowsiness: As a first-generation antihistamine, cinnarizine can cause drowsiness, making it effective for treating nausea and vertigo but also potentially impairing motor coordination.

Indications:

Cinnarizine (Cinnarex) 25mg tablets are used for the following conditions:

1. Motion Sickness:

   • Cinnarizine is commonly used to prevent or treat symptoms of motion sickness, such as nausea, vomiting, and dizziness, associated with travel (e.g., by car, plane, boat, or train).

2. Vertigo:

   • It is used to treat vertigo (a sensation of spinning or dizziness) caused by conditions like Ménière’s disease or other vestibular disorders, which affect the inner ear's balance mechanism.

3. Nausea and Vomiting:

   • Used to reduce nausea and vomiting caused by various conditions, including post-surgery or illness.

4. Inner Ear Disorders:

   • Cinnarizine helps alleviate symptoms associated with balance disturbances due to disorders of the inner ear.

Dosage:

The general dosage for Cinnarizine (Cinnarex) 25mg tablets in adults is as follows:

• For Motion Sickness:

  • Adults and children over 12 years: 25mg (1 tablet) taken 30 minutes before travel. If necessary, the dose can be repeated every 6 to 8 hours. Do not exceed 3 tablets per day.

• For Vertigo and Balance Disorders:

  • Adults: Start with 25mg (1 tablet) up to 3 times per day, depending on the severity of symptoms. The dose can be adjusted by your doctor based on your individual needs.

• For Children (6-12 years):

  • 5mg to 10mg (half or one tablet) taken once to twice daily, depending on the doctor’s recommendation.

Administration:

• Take the tablets orally with or without food, usually with a full glass of water.

• It is typically recommended to take the tablet before symptoms of motion sickness or vertigo appear for the best effect.

Side Effects:

Common side effects of Cinnarizine (Cinnarex) 25mg tablets include:

• Drowsiness or sedation (most common with first-generation antihistamines).

• Dry mouth, throat, or nose.

• Headache.

• Fatigue or feeling unusually tired.

• Gastrointestinal issues such as nausea, indigestion, or constipation.

Less common but more serious side effects may include:

• Dizziness or lightheadedness (especially in elderly patients).

• Blurred vision.

• Confusion, especially in older individuals.

• Tremors or restlessness.

• Allergic reactions: Symptoms such as rash, itching, swelling of the face, lips, or tongue (which requires immediate medical attention).

If any of these serious side effects occur, seek medical advice immediately.

Contraindications:

Cinnarizine (Cinnarex) should not be used in the following cases:

1. Hypersensitivity:

   • If the patient is allergic to Cinnarizine or any of its ingredients.

2. Severe Liver Impairment:

   • Cinnarizine should be used with caution in patients with severe liver disease or hepatic impairment.

3. Pregnancy:

   • Cinnarizine is classified as Category C for pregnancy, which means that it should only be used if the benefits outweigh the risks. It is generally advised to avoid it during the first trimester unless recommended by a healthcare provider.

4. Breastfeeding:

   • Cinnarizine passes into breast milk, so it should be avoided or used with caution in breastfeeding mothers. Consult your doctor before using this medication while breastfeeding.

5. Children under 6 years:

   • It is not recommended for children younger than 6 years, as safety and efficacy have not been established.

6. Severe Kidney Impairment:

   • Caution should be exercised in patients with kidney disease or impairment, as dosage adjustments may be required.

Warnings and Precautions:

• Drowsiness: Since cinnarizine can cause drowsiness, it is important not to engage in activities that require mental alertness, such as driving or operating machinery, after taking this medication.

• Alcohol: Avoid alcohol as it can increase the sedative effects of cinnarizine.

• Elderly patients: Older adults are more susceptible to side effects like confusion, dizziness, and drowsiness. They should use this medication with caution.

• Glaucoma: Use with caution in patients with narrow-angle glaucoma.

• Prostate enlargement: Use with caution in patients with prostatic hypertrophy due to the anticholinergic effects of cinnarizine.

Drug Interactions:

• Alcohol: Alcohol can enhance the sedative effects of cinnarizine, leading to excessive drowsiness and impaired coordination.

• CNS Depressants: Using cinnarizine with other central nervous system (CNS) depressants (like benzodiazepines, opioids, or sleeping pills) may result in increased sedation or drowsiness.

• Anticholinergic Drugs: Cinnarizine may add to the effects of other anticholinergic drugs, which could cause increased dry mouth, constipation, and urinary retention.

Storage:

• Store at room temperature (15°C to 30°C), away from direct sunlight and moisture.

• Keep the tablets in their original packaging and ensure they are kept in a cool, dry place.

• Keep out of the reach of children.

• Do not use the tablets after the expiry date listed on the packaging.

Conclusion:

Cinnarizine (Cinnarex) 25mg Tablets are a widely used treatment for motion sickness, vertigo, and balance-related issues. This antihistamine is effective in reducing dizziness, nausea, and vomiting caused by various conditions, and its sedative properties can help alleviate symptoms of motion sickness. However, it should be used with caution, particularly in older adults, pregnant or breastfeeding women, and those with liver or kidney issues. Always follow the prescribed dosage and consult a healthcare provider if you have any concerns or experience adverse effects.