Dicycloverine Hydrochloride (Gasaide) 10mg Tablet 100's

Certainly! Below is the detailed information for Dicycloverine Hydrochloride (Gasaide) 10mg Tablet 100's:

Product Description:

Dicycloverine Hydrochloride (Gasaide) is a medication used to relieve smooth muscle spasms, particularly in the gastrointestinal tract. It is an anticholinergic drug that works by blocking the action of acetylcholine, a neurotransmitter responsible for muscle contraction. This results in the relaxation of smooth muscles, thereby reducing spasms and relieving discomfort.

The Gasaide 10mg tablet is typically sold in a pack of 100 tablets and is used for the symptomatic relief of gastrointestinal disorders associated with smooth muscle spasms, such as irritable bowel syndrome (IBS) and functional gastrointestinal disorders.

Indications:

Dicycloverine Hydrochloride (Gasaide) is primarily indicated for the following conditions:

• Irritable Bowel Syndrome (IBS): To relieve abdominal cramps, bloating, and discomfort associated with IBS.

• Gastrointestinal Spasms: Used to treat spasms of the stomach, intestines, or bladder, often due to gastrointestinal disorders or after surgery.

• Functional Gastrointestinal Disorders: Such as dyspepsia, where there are no clear organic causes for symptoms but muscle spasms cause discomfort.

• Other Conditions Involving Smooth Muscle Spasms: Dicycloverine may be prescribed for other conditions where the smooth muscles of the gastrointestinal tract or urinary tract are overactive.

Dosage:

The usual dosage of Dicycloverine Hydrochloride (Gasaide) depends on the patient’s condition and age. The typical dosage for adults and children over 12 years is as follows:

• For Adults:

  • Initial Dose: 10mg orally, taken three to four times a day.

  • Maintenance Dose: The dose can be increased based on the patient’s response, typically up to 20mg, three times a day, but this should be determined by a healthcare provider.

• For Children (6 to 12 years):

  • Dose: 5mg taken two to three times a day. However, the dosage should be determined and monitored by a healthcare provider.

• For Elderly Patients: Dosage adjustments may be necessary, starting at the lower end of the dosing range to avoid excessive side effects like dry mouth and dizziness.

Important Note: Always follow your healthcare provider’s instructions for dosing. If you miss a dose, take it as soon as you remember unless it’s almost time for your next dose. Do not double up on doses to make up for a missed dose.

Side Effects:

Common side effects of Dicycloverine Hydrochloride (Gasaide) may include:

• Dry mouth: A common side effect due to the anticholinergic effect of dicycloverine.

• Dizziness or lightheadedness: Especially when standing up quickly, due to the relaxation of smooth muscles.

• Blurred vision: Due to the anticholinergic effects, which can cause pupil dilation.

• Constipation: A decrease in gastrointestinal motility can lead to constipation.

• Nausea or vomiting: Some individuals may experience gastrointestinal discomfort.

• Urinary retention: Difficulty urinating, especially in patients with enlarged prostate.

Less common but more serious side effects include:

• Confusion or memory problems: More common in elderly patients or when taken in higher doses.

• Tachycardia (fast heart rate): Can occur, particularly in high doses.

• Allergic reactions: Rare but serious, including swelling of the face, lips, throat, and difficulty breathing.

• Paralytic ileus (intestinal paralysis): This rare side effect may occur with high doses, causing the bowel to stop moving.

If you experience any of these serious side effects, seek immediate medical attention.

Contraindications:

Dicycloverine Hydrochloride (Gasaide) should not be used in the following conditions:

• Hypersensitivity to Dicycloverine or any of the excipients: If you have an allergy to Dicycloverine or any of the ingredients, you should not use this medication.

• Glaucoma: Dicycloverine may increase intraocular pressure, which can exacerbate closed-angle glaucoma.

• Myasthenia Gravis: A condition where muscle weakness occurs. Dicycloverine can worsen muscle weakness in these patients.

• Severe Ulcerative Colitis or Megacolon: It can worsen these conditions due to its anticholinergic effects, which reduce gastrointestinal motility.

• Bowel Obstruction: Dicycloverine should not be used in patients with bowel obstruction or a history of ileus (intestinal paralysis).

• Severe Urinary Retention: In patients with urinary retention, particularly those with prostatic hypertrophy (enlarged prostate), dicycloverine can worsen symptoms.

• Severe Heart Disease: Use with caution in patients with tachycardia, arrhythmias, or heart failure, as dicycloverine may exacerbate heart rate issues.

Precautions:

• Elderly Patients: Older adults are particularly sensitive to the side effects of anticholinergic drugs, such as confusion, constipation, and urinary retention. Lower doses may be necessary, and close monitoring is recommended.

• Renal or Hepatic Impairment: Caution is advised in patients with kidney or liver disease. Dosage adjustments may be necessary to avoid accumulation of the drug.

• Pregnancy and Breastfeeding: While the safety of Dicycloverine during pregnancy has not been fully established, it should only be used if the potential benefit outweighs the risk. It is not recommended during breastfeeding, as it can pass into breast milk.

• Intestinal Obstruction: In patients with partial obstruction, Dicycloverine should be used cautiously, as it can reduce gastrointestinal motility and worsen the condition.

• Diabetes: Dicycloverine can cause dry mouth, which may complicate the management of oral hygiene in diabetic patients.

Drug Interactions:

• Other Anticholinergic Medications: Combining Dicycloverine with other drugs that have anticholinergic effects (such as antihistamines, tricyclic antidepressants, and antipsychotics) can enhance side effects like dry mouth, blurred vision, constipation, and urinary retention.

• CNS Depressants: Concurrent use with sedatives or alcohol may increase the risk of drowsiness and dizziness.

• Antihypertensive Drugs: Dicycloverine may enhance the effects of medications used to lower blood pressure, especially if used in combination with other medications that can cause drowsiness or dizziness.

Summary:

Dicycloverine Hydrochloride (Gasaide) 10mg Tablet is an anticholinergic medication primarily used to relieve gastrointestinal and urological smooth muscle spasms. It is commonly prescribed for Irritable Bowel Syndrome (IBS) and other conditions that involve muscle cramps or discomfort in the abdominal area. The standard dosage is 10mg, taken 3-4 times a day, depending on the patient's response and severity of symptoms.

While effective, Dicycloverine can cause side effects like dry mouth, dizziness, blurred vision, and constipation. It should be used cautiously in elderly patients and those with certain conditions, such as glaucoma, myasthenia gravis, or urinary retention. Always follow the prescribed dosage and consult a healthcare provider for personalized advice and guidance.

For more specific concerns or questions about its use, it's important to talk to your healthcare provider.