Lidocaine Hydrochloride 20mg/ml Solution For Injection Local Anesthetic 50ml

Generic Name: LIDOCAINE HYDROCHLORIDE

Brand Name: LIDOPHIL

Strength: 20mg/mL (2% w/v)

Form: SOLUTION FOR INJECTION

Manufacturer: HEBEI TIANCHENG PHARMACEUTICAL CO., LTD.

Imported and Distributed by: PHILRX PHARMA INC.

Classification: LOCAL ANESTHETIC

Indication/Uses: 

1. Local Anesthesia

   • Minor Surgical Procedures: Lidocaine is used to induce local anesthesia for minor surgical procedures, such as suturing wounds, dental procedures, or minor skin surgeries. It numbs the targeted area, providing pain relief during and immediately after the procedure.
   • Diagnostic Procedures: Applied in procedures like lumbar punctures and biopsies to minimize patient discomfort.
   • Obstetric Procedures: Utilized in labor and delivery for procedures such as episiotomies.

2. Regional Anesthesia

   • Nerve Blocks: Lidocaine can be used for peripheral nerve blocks, which involve injecting the anesthetic near a specific nerve or group of nerves to block sensations in a particular area of the body.
   • Epidural and Spinal Anesthesia: Administered in the epidural space of the spine, providing anesthesia for surgeries involving the lower limbs, pelvis, and abdomen.

3. Antiarrhythmic Use

   • Ventricular Arrhythmias: Lidocaine is used intravenously in emergency settings to treat acute ventricular arrhythmias, particularly after a myocardial infarction (heart attack). It helps stabilize the heart's rhythm by inhibiting abnormal electrical activity.

Mechanism of Action

Lidocaine works by blocking sodium channels on nerve cell membranes, preventing the initiation and transmission of nerve impulses. This action numbs the area where it is applied, providing effective local anesthesia. When used as an antiarrhythmic, lidocaine stabilizes the cardiac cell membrane, reducing the excitability of heart muscle cells and helping to restore normal heart rhythm.

Dosage and Administration

• Local Anesthesia: The dosage varies depending on the type and extent of the procedure. Typical concentrations for local anesthesia range from 0.5% to 2%.
• Nerve Blocks: Dosages are higher and adjusted based on the site and nature of the block.
• Antiarrhythmic: When used for ventricular arrhythmias, it is typically administered as a 1-1.5 mg/kg bolus intravenously, followed by a continuous infusion.