Naproxen Sodium (Saphroxen 550) 550mg Film Coated Tablet 100's

Generic Name: Naproxen Sodium

Brand Name: Saphroxen 550

Strength: 550mg

Form: Tablet

Manufacturer:

Imported and Distributed by:

Classification: Anti Inflammatory

Indication/Uses:

Naproxen Sodium (Saphroxen 550) 550mg Film Coated Tablet is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce inflammation. Here are the primary indications and uses:

Indications and Uses

1. Pain Relief:

   • Mild to Moderate Pain: Effective in treating mild to moderate pain from various causes, including musculoskeletal pain, dental pain, and headache.
   • Postoperative Pain: Used for the management of pain following surgical procedures.

2. Inflammatory Conditions:

   • Rheumatoid Arthritis: Reduces inflammation, pain, and stiffness in rheumatoid arthritis.
   • Osteoarthritis: Alleviates pain and inflammation associated with osteoarthritis.
   • Ankylosing Spondylitis: Helps manage pain and inflammation in ankylosing spondylitis.

3. Musculoskeletal Disorders:

   • Tendinitis and Bursitis: Relieves pain and inflammation in tendinitis and bursitis.
   • Acute Gout: Reduces pain and inflammation in acute gout attacks.

4. Dysmenorrhea:

   • Menstrual Pain: Provides relief from pain and cramps associated with primary dysmenorrhea.

Mechanism of Action

• Inhibition of Prostaglandin Synthesis: Naproxen works by inhibiting the enzymes cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), which are involved in the production of prostaglandins. Prostaglandins are chemicals in the body that cause inflammation, pain, and fever. By reducing their production, naproxen alleviates pain and inflammation.

Dosage and Administration

• Dosage: The dosage varies based on the condition being treated and the patient's response.
  • Adults: The usual dose is one 550mg tablet initially, followed by 275mg to 550mg every 12 hours as needed. Do not exceed a total daily dose of 1,375mg (2.5 tablets).
• Administration: Take the tablet with a full glass of water. It can be taken with food or milk to minimize gastrointestinal discomfort.

Instructions for Use

1. Regular Use:

   • Take naproxen exactly as prescribed by a healthcare provider.
   • For chronic conditions, use consistently to maintain its anti-inflammatory effect.

2. Missed Dose:

   • If a dose is missed, take it as soon as remembered. If it is close to the time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not take a double dose to make up for the missed one.

Precautions

• Gastrointestinal Risk: NSAIDs, including naproxen, can cause serious gastrointestinal adverse events such as bleeding, ulceration, and perforation of the stomach or intestines. These events can occur at any time during use and without warning symptoms.
• Cardiovascular Risk: NSAIDs may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. The risk may increase with duration of use.
• Kidney Function: Use with caution in patients with impaired kidney function, as NSAIDs can reduce renal blood flow and compromise renal function.
• Pregnancy and Lactation: Consult a healthcare provider before using naproxen during pregnancy or breastfeeding.

Side Effects

• Common: Nausea, heartburn, dizziness, headache, and abdominal pain.
• Serious: Gastrointestinal bleeding, ulcers, hypertension, heart attack, stroke, kidney damage, and severe allergic reactions (e.g., rash, itching, swelling, dizziness, difficulty breathing).

Monitoring

• Effectiveness: Monitor for improvements in pain and inflammation.
• Adverse Effects: Regularly assess for any side effects, particularly gastrointestinal and cardiovascular symptoms, and report them to a healthcare provider immediately.

Naproxen Sodium (Saphroxen 550) 550mg Film Coated Tablet is used for the relief of pain and inflammation in various conditions. Proper use, adherence to dosing schedules, and monitoring for side effects are essential to ensure the medication's effectiveness and safety.