Bambang Pharmaceutical Depot Inc.
Tranexamic Acid (Haemorex) 500mg Capsule 100's
Tranexamic Acid (Haemorex) 500mg Capsule 100's
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Certainly! Here's the detailed information for Tranexamic Acid (Haemorex) 500mg Capsule 100's:
Product Description:
Tranexamic Acid (Haemorex) is a synthetic antifibrinolytic agent that works by inhibiting the breakdown of fibrin, a protein essential for blood clotting. It blocks the action of plasminogen activators, which are involved in the conversion of plasminogen to plasmin, the enzyme responsible for dissolving blood clots. By preventing the dissolution of clots, Tranexamic Acid helps reduce excessive bleeding.
Each Tranexamic Acid (Haemorex) capsule contains 500 mg of Tranexamic Acid. The pack contains 100 capsules.
Indications:
Tranexamic Acid (Haemorex) is indicated for the treatment of conditions involving abnormal or excessive bleeding. Common uses include:
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Heavy Menstrual Bleeding (Menorrhagia):
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Used to control and reduce heavy menstrual bleeding in women.
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Post-Surgical Bleeding:
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Used to reduce bleeding and complications in patients undergoing surgery (e.g., dental, orthopedic, or cardiac surgery).
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Trauma-Related Bleeding:
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Used in trauma cases where significant bleeding is present, including trauma-induced hemorrhage.
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Bleeding Disorders:
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Used to manage bleeding associated with certain disorders, including hemophilia, von Willebrand disease, and postpartum hemorrhage.
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Nasal Bleeding (Epistaxis):
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Used in the management of epistaxis (nosebleeds), especially in chronic or recurrent cases.
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Other Conditions:
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Can be used to control bleeding in conditions like postpartum hemorrhage, bleeding after surgery, or after dental extractions in patients with bleeding disorders.
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Dosages:
The recommended dosage of Tranexamic Acid (Haemorex) depends on the condition being treated:
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For Heavy Menstrual Bleeding (Menorrhagia):
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Adults: Take 1 capsule (500 mg) 3 times a day for 5 days, starting from the first day of menstruation.
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If necessary, the dose may be adjusted by a healthcare provider.
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For Post-Surgical Bleeding (e.g., dental or orthopedic surgery):
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Adults: Take 1 to 2 capsules (500 mg to 1000 mg) every 8 hours for up to 5 days after surgery, depending on the type and severity of bleeding.
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For Trauma-Related Bleeding:
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Adults: Typically 1 to 2 capsules (500 mg to 1000 mg) every 8 hours until bleeding is controlled, usually within 24 to 48 hours.
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For Epistaxis (Nosebleeds):
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Adults: The dose may be 500 mg to 1000 mg every 8 hours for short-term control, depending on the frequency and severity of nosebleeds.
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For Other Conditions:
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The dosage for conditions like postpartum hemorrhage or bleeding due to medical procedures should be determined by the healthcare provider, based on the individual patient's needs.
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Note: Always follow your healthcare provider's instructions regarding dosage, especially if it is for long-term or chronic conditions.
Side Effects:
Like all medications, Tranexamic Acid (Haemorex) may cause side effects, although not everyone will experience them. Some potential side effects include:
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Common Side Effects:
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Nausea or vomiting.
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Diarrhea or stomach upset.
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Headache.
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Dizziness or lightheadedness.
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Muscle pain or discomfort.
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Serious Side Effects (less common but require immediate medical attention):
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Thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism, stroke): This is a rare but serious risk due to the potential for increased blood clotting.
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Severe allergic reactions: Symptoms may include rash, itching, swelling of the face, tongue, or throat, and difficulty breathing.
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Visual disturbances: Some individuals may experience blurry vision or color vision changes, especially with prolonged use.
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Severe gastrointestinal symptoms: Severe abdominal pain, constipation, or black tarry stools.
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Chest pain or shortness of breath, which may indicate a serious complication like a blood clot.
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Other Side Effects:
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Fatigue or weakness.
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Back pain or muscle stiffness.
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Skin rash or redness.
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If you experience any of these more serious side effects, discontinue use and seek immediate medical help.
Contraindications:
Tranexamic Acid (Haemorex) should not be used in the following conditions:
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Hypersensitivity:
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Contraindicated in individuals who have a known allergy to Tranexamic Acid or any of its ingredients.
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Active or History of Blood Clotting Disorders:
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Tranexamic Acid is contraindicated in patients with a history of deep vein thrombosis (DVT), pulmonary embolism (PE), or stroke, as it can increase the risk of blood clots.
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Subarachnoid Hemorrhage:
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Tranexamic Acid should not be used in patients with a subarachnoid hemorrhage (bleeding in the brain), as it may increase the risk of worsening bleeding.
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Severe Kidney Dysfunction:
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Contraindicated in patients with severe renal impairment or acute kidney failure because Tranexamic Acid is eliminated through the kidneys and may cause accumulation in the body.
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Active Bleeding:
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Should not be used in individuals with active bleeding from the gastrointestinal tract, or other sites where blood clots could be harmful.
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Pregnancy and Breastfeeding:
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Tranexamic Acid should only be used during pregnancy if absolutely necessary and prescribed by a doctor. It is Category B in pregnancy, meaning there is limited evidence of risk. Consult a healthcare provider if you are pregnant or breastfeeding.
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Severe Liver Dysfunction:
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Use with caution in individuals with liver disease or liver dysfunction, as it can affect how the medication is metabolized.
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Warnings and Precautions:
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Risk of Thromboembolic Events:
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Tranexamic Acid may increase the risk of blood clot formation (thromboembolism). Caution is advised in patients with a history of clotting disorders, or those who are at increased risk for clots (e.g., immobile patients, those with recent surgery, or those with heart conditions).
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Renal Function:
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Tranexamic Acid should be used with caution in patients with renal impairment. Kidney function should be monitored in such patients, as the drug is primarily excreted through the kidneys.
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Women with Menorrhagia:
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It is important to rule out underlying causes of heavy menstrual bleeding (such as uterine fibroids or other pathology) before starting Tranexamic Acid for menorrhagia.
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Visual Disturbances:
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If you notice any visual changes (e.g., blurry vision or changes in color perception), contact your healthcare provider, as this could indicate a serious side effect, especially with prolonged use.
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Drug Interactions:
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Tranexamic Acid may interact with other medications, particularly those that affect blood clotting (e.g., anticoagulants, antiplatelet agents, fibrinolytic agents). Close monitoring is required if used alongside such medications.
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Pregnancy:
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As mentioned, the medication should only be used in pregnancy when the benefits outweigh the risks. Always consult your doctor before use.
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Storage:
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Store Tranexamic Acid (Haemorex) at room temperature (15°C to 25°C), away from moisture and direct sunlight.
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Keep out of the reach of children.
Important Note: Always take Tranexamic Acid (Haemorex) exactly as prescribed by your healthcare provider. Do not take more than the recommended dose, and report any unusual symptoms or side effects to your doctor immediately.
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