Generic Name: Mebendazole

Brand Name: Khrizver

Strength: 500mg

Form: Tablet

Manufacturer:

Imported and Distributed by:

Classification: Anthelmintic

Indication/Uses:

Mebendazole (Khrizver) 500mg "Orange Flavor" Chewable Tablets are used for the treatment of various parasitic worm infections. Here are the indications and uses:

Indications and Uses

1. Intestinal Worm Infections:

   • Ascariasis: Infection caused by Ascaris lumbricoides (roundworm).
   • Trichuriasis: Infection caused by Trichuris trichiura (whipworm).
   • Hookworm Infection: Caused by Ancylostoma duodenale or Necator americanus.
   • Enterobiasis: Infection caused by Enterobius vermicularis (pinworm).
   • Strongyloidiasis: Infection caused by Strongyloides stercoralis.
   • Mixed Infections: Effective for infections caused by more than one type of worm simultaneously.

2. Other Uses:

   • Prevention: Sometimes used as a preventive treatment in areas with high prevalence of worm infections.

Mechanism of Action

• Antihelminthic: Mebendazole works by inhibiting the formation of microtubules in the parasitic worms, leading to their immobilization and death. It disrupts the worms' ability to absorb glucose, leading to their energy depletion and eventual death.

Dosage and Administration

• Dosage:

  • Adults and Children Over 2 Years: The usual dose is 500mg as a single dose for most intestinal worm infections. For severe infections, the dose may be repeated after 3 weeks or as directed by a healthcare provider.
  • Children (under 2 years): Consult a healthcare provider for appropriate dosage.

• Administration:

  • Chew the tablet thoroughly before swallowing. The "orange flavor" is intended to make the tablet more palatable.

Instructions for Use

1. Regular Use:

   • Follow the prescribed dosage and schedule as directed by a healthcare provider.

2. Missed Dose:

   • Since Mebendazole is often given as a single dose, missing a dose may not be an issue. If a dose is missed, contact a healthcare provider for advice.

Precautions

• Allergic Reactions: Ensure there are no known allergies to Mebendazole or other anthelmintic medications.
• Pregnancy and Breastfeeding: Consult a healthcare provider before using Mebendazole during pregnancy or breastfeeding.
• Liver and Kidney Function: Use with caution in individuals with liver or kidney impairment.

Side Effects

• Common: Mild gastrointestinal symptoms such as nausea, vomiting, abdominal pain, or diarrhea.
• Serious: Rare but may include severe allergic reactions like rash, itching, swelling, or difficulty breathing. If any severe side effects occur, seek medical attention immediately.

Storage

• Storage: Store tablets in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.

Mebendazole (Khrizver) 500mg "Orange Flavor" Chewable Tablets are effective for treating a variety of intestinal worm infections. Adhering to the prescribed dosage and administration instructions ensures effectiveness and helps minimize potential side effects.