Generic Name: TRETINOIN

Brand Name: ACNECARE

Strength: 250mcg/g 0.025%

Form: CREAM

Manufacturer: YASH MEDICARE PRIVATE LIMITED 

Imported and Distributed by: AGLOBAL CARE, INC.

Classification: ANTI-ACNE

Indication/Uses: 

Indications:

1. Acne Vulgaris:

   • Tretinoin is primarily indicated for the topical treatment of acne vulgaris. It works by promoting cell turnover and preventing the formation of new acne lesions. It helps to reduce the number and severity of acne pimples and promotes quick healing of pimples that do develop.

2. Photodamaged Skin:

   • It is also used for the treatment of photodamaged skin, which includes conditions such as fine wrinkles, rough patches, and hyperpigmentation. Tretinoin helps improve skin texture and tone by stimulating collagen production and increasing cell turnover.

3. Hyperpigmentation Disorders:

   • Tretinoin can be used to treat hyperpigmentation disorders like melasma and age spots. It helps to lighten the dark spots and even out skin tone.

Uses:

1. Skin Renewal:

   • Tretinoin is a retinoid that helps promote skin cell turnover, shedding old skin cells and making way for new ones. This process helps to clear up acne and reduce the appearance of fine lines and wrinkles.

2. Anti-Aging:

   • Regular use of tretinoin can help reduce signs of aging by minimizing the appearance of fine lines, wrinkles, and age spots. It increases collagen production in the dermis, leading to firmer and smoother skin.

3. Treatment of Keratosis Pilaris:

   • Tretinoin is sometimes used off-label to treat keratosis pilaris, a condition that causes rough patches and small, acne-like bumps on the skin.

Mechanism of Action:

• Tretinoin works by binding to retinoic acid receptors in the skin, which then influence gene expression in keratinocytes (skin cells). This action increases the rate of cell turnover, reduces the cohesion of skin cells, and promotes the expulsion of comedones (blackheads and whiteheads).

Dosage and Administration:

• Tretinoin cream should be applied once daily, preferably in the evening. The affected area should be cleaned and dried before application. A pea-sized amount is typically sufficient for the entire face.