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Bambang Pharmaceutical Depot Inc.

Aluminum Hydroxide + Magnesium Hydroxide (Neutrasaph) 200mg/100mg per 5ml Suspension 60ml

Aluminum Hydroxide + Magnesium Hydroxide (Neutrasaph) 200mg/100mg per 5ml Suspension 60ml

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Below is the detailed product description, indications, dosages, side effects, and contraindications for Aluminum Hydroxide + Magnesium Hydroxide (Neutrasaph) 200mg/100mg per 5ml Suspension 60ml:


Product Description:

Neutrasaph Suspension contains Aluminum Hydroxide (200mg) and Magnesium Hydroxide (100mg) per 5ml of suspension. It is an antacid formulation used for the relief of symptoms related to gastrointestinal acidity. The combination of Aluminum Hydroxide and Magnesium Hydroxide works to neutralize excess stomach acid, providing relief from conditions such as heartburn, acid indigestion, and sour stomach. The 60ml suspension comes in a bottle for easy dosing, making it suitable for both adults and children under appropriate guidance.

  • Aluminum Hydroxide acts by neutralizing gastric acid and forming a gel-like substance that coats the stomach lining, reducing irritation.

  • Magnesium Hydroxide works similarly by neutralizing excess stomach acid and also has a mild laxative effect to counteract the constipation that can sometimes be caused by aluminum-containing antacids.

The product is commonly used for the short-term relief of acid reflux, gastric ulcers, dyspepsia (indigestion), and other conditions associated with excess stomach acid.


Indications:

Neutrasaph Suspension is primarily indicated for the symptomatic relief of the following conditions:

  1. Gastroesophageal Reflux Disease (GERD):

    • Helps to reduce heartburn and other symptoms of acid reflux.

  2. Acid Indigestion:

    • Used to relieve symptoms of acid indigestion or sour stomach.

  3. Gastric Ulcers:

    • Provides symptomatic relief in conditions like gastric ulcers and peptic ulcers, where excess stomach acid is a contributing factor.

  4. Dyspepsia (Indigestion):

    • Alleviates the discomfort associated with indigestion, including bloating, belching, and mild stomach pain.

  5. Relief from Excessive Stomach Acid:

    • Neutralizes excess stomach acid, helping to manage discomfort caused by hyperacidity.

  6. Preventing Constipation due to Aluminum-based Antacids:

    • Magnesium Hydroxide in the formulation helps to prevent constipation, a common side effect of aluminum-based antacids.


Dosages:

The recommended dose of Neutrasaph Suspension depends on the age of the patient and the severity of symptoms. The usual dosage is:

For Adults and Children Over 12 Years:

  • 10 to 20ml three to four times a day, after meals and at bedtime.

  • Shake the bottle well before use to ensure the suspension is evenly mixed.

For Children (6 to 12 Years):

  • 5 to 10ml three to four times a day, after meals and at bedtime.

For Children (Under 6 Years):

  • Consult a healthcare provider for the appropriate dosage. Typically, it is not recommended for young children unless prescribed by a doctor.

Note: Dosage should not exceed the recommended daily limit unless instructed by a healthcare professional.


Side Effects:

While Neutrasaph Suspension is generally well-tolerated, some side effects may occur. Common side effects include:

Common Side Effects:

  • Diarrhea: Magnesium Hydroxide can have a mild laxative effect, which may result in loose stools.

  • Constipation: In some cases, Aluminum Hydroxide may cause constipation, though this is less likely due to the magnesium content.

  • Stomach discomfort: Some individuals may experience mild bloating, gas, or nausea.

  • Changes in bowel habits: Due to the magnesium content, diarrhea or loose stools may occur.

Serious Side Effects (Rare):

  • Electrolyte imbalances: Prolonged use of antacids like this product can result in magnesium toxicity or low calcium levels. Symptoms may include muscle weakness, irregular heartbeats, or confusion.

  • Kidney problems: Individuals with kidney disease may be at increased risk of magnesium toxicity or aluminum accumulation.

  • Allergic reactions: Though rare, symptoms like rash, itching, swelling of the face or throat, or difficulty breathing may indicate an allergic reaction. Seek immediate medical help if this occurs.


Contraindications:

Neutrasaph Suspension should not be used or should be used with caution in the following conditions:

  1. Hypersensitivity to the Ingredients:

    • Neutrasaph should be avoided by individuals who are allergic or hypersensitive to Aluminum Hydroxide, Magnesium Hydroxide, or any other components of the formulation.

  2. Severe Kidney Impairment:

    • Individuals with severe renal (kidney) impairment should avoid this product, as magnesium and aluminum can accumulate in the body, leading to toxicity.

  3. Hypermagnesemia (High Magnesium Levels):

    • This product should be avoided in individuals with existing high magnesium levels, as Magnesium Hydroxide can further raise these levels and cause severe side effects.

  4. Hyperphosphatemia (High Phosphate Levels):

    • Use with caution in individuals with elevated phosphate levels, as Aluminum Hydroxide may interfere with phosphate metabolism.

  5. Pregnancy and Breastfeeding:

    • Neutrasaph should be used during pregnancy only if the potential benefits outweigh the risks. Always consult with a healthcare provider before using this product during pregnancy or lactation.

    • While this medication is generally considered safe for short-term use during breastfeeding, it is important to consult a healthcare provider before using it.

  6. Children Under 6 Years:

    • The use of this medication in children under the age of 6 years should be done only under the guidance of a healthcare professional, as the safety profile for very young children may differ.


Precautions:

  1. Prolonged Use:

    • Long-term use of antacids, including Neutrasaph, can lead to electrolyte imbalances and kidney problems, especially in patients with pre-existing kidney issues. It is important to monitor for symptoms of magnesium toxicity or aluminum toxicity with prolonged use.

  2. Interaction with Other Medications:

    • Neutrasaph can interact with certain medications, including tetracycline antibiotics, fluoroquinolone antibiotics, and iron supplements. It may reduce the absorption of these drugs, so it is important to space out dosing of Neutrasaph and other medications by at least 2 hours.

  3. Pregnancy:

    • Neutrasaph should only be used during pregnancy if absolutely necessary. Always consult with a healthcare provider before taking this or any medication during pregnancy.

  4. Dosage Adjustment in Kidney Disease:

    • If you have kidney disease or renal impairment, speak to your doctor before using this product, as it may not be suitable for your condition due to the potential for aluminum and magnesium accumulation.


Summary:

Neutrasaph (Aluminum Hydroxide + Magnesium Hydroxide) is an antacid suspension used to provide relief from acid indigestion, heartburn, gastric ulcers, and dyspepsia. The combination of Aluminum Hydroxide and Magnesium Hydroxide works by neutralizing stomach acid and can also help to relieve symptoms of gastroesophageal reflux disease (GERD).

  • Indications: Relief from heartburn, gastric ulcers, indigestion, and other acid-related symptoms.

  • Dosage: Typically 10-20ml three to four times a day, depending on age and severity.

  • Side Effects: Common effects include gastrointestinal discomfort like diarrhea and constipation. Serious side effects are rare but may include electrolyte imbalances and kidney problems.

  • Contraindications: Kidney disease, hypersensitivity, hypermagnesemia, and children under 6 years.

Always follow the recommended dosing instructions and consult with a healthcare provider if you have any underlying conditions, are pregnant or breastfeeding, or are taking other medications.

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