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Bambang Pharmaceutical Depot Inc.

Amlodipine (Amlosaph) Calcium channel Blocker 10mg 100's

Amlodipine (Amlosaph) Calcium channel Blocker 10mg 100's

Regular price ₱100.00 PHP
Regular price ₱250.00 PHP Sale price ₱100.00 PHP
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Generic Name: AMLODIPINE

Brand Name: AMLOSAPH-10

Strength: 10mg

Form: Tablet


Imported and Distributed by: NELPA LIFESCIENCES, INC.



Amlodipine, branded as Amlosaph, is a calcium channel blocker that is commonly prescribed for the following conditions:

  1. Hypertension (High Blood Pressure):

    • Amlodipine helps to lower blood pressure by relaxing the blood vessels, allowing blood to flow more easily. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.
  2. Angina (Chest Pain):

    • It is used to prevent certain types of chest pain (angina). By relaxing the blood vessels and improving blood flow to the heart muscle, it helps to relieve chest pain and reduce the frequency and severity of angina attacks.
  3. Coronary Artery Disease:

    • Amlodipine can be used to improve survival and reduce the risk of heart attack in patients with certain types of coronary artery disease.


  • Typical Starting Dose:
    • The initial dose for adults is usually 5 mg once daily, which may be increased to a maximum dose of 10 mg once daily depending on the patient’s response and tolerance.

Mechanism of Action

Amlodipine belongs to the class of drugs known as calcium channel blockers. It works by inhibiting the movement of calcium ions into the smooth muscle cells of the heart and blood vessels. This results in the dilation of blood vessels and a reduction in blood pressure. It also decreases the heart’s workload by reducing the force of contraction and oxygen demand.


  • Oral Use:
    • Amlodipine tablets are taken orally, with or without food. It is important to take it at the same time each day to maintain an even level of the medication in your blood.

Side Effects

Common side effects may include:

  • Swelling (edema) of the ankles or feet
  • Headache
  • Dizziness
  • Flushing (feeling of warmth)
  • Fatigue


  • Allergy:
    • Avoid if you have a known allergy to amlodipine or any other dihydropyridine calcium channel blockers.
  • Severe Aortic Stenosis:
    • Use with caution in patients with severe aortic stenosis as it can lead to increased risk of hypotension.
  • Hepatic Impairment:
    • Dose adjustment may be necessary in patients with liver problems.


Amlodipine may interact with other medications, such as:

  • Other antihypertensive agents (increased risk of hypotension)
  • Simvastatin (may increase the risk of simvastatin side effects)
  • Grapefruit juice (can increase the blood levels of amlodipine and exacerbate side effects)


  • Regular monitoring of blood pressure is recommended to ensure the medication is effective.
  • Periodic liver function tests may be advised for patients with liver disease.

Always consult a healthcare provider for personalized medical advice and before starting or stopping any medication.

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