Bambang Pharmaceutical Depot Inc.
Ampicillin Sodium (Liferzin) 1g Powder for Injection I.V/I.M Vials 10's
Ampicillin Sodium (Liferzin) 1g Powder for Injection I.V/I.M Vials 10's
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Here is a detailed overview of Ampicillin Sodium (Liferzin) 1g Powder for Injection I.V/I.M Vials 10's:
Product Description:
Liferzin (Ampicillin Sodium) is an antibiotic that belongs to the penicillin class of medications. It is used to treat a variety of bacterial infections by inhibiting the growth of bacteria. The product comes in the form of a 1g powder for injection, which can be reconstituted and administered either intravenously (I.V.) or intramuscularly (I.M.). Each pack contains 10 vials of 1g each.
Ampicillin is a broad-spectrum antibiotic that is effective against a wide range of Gram-positive and Gram-negative bacteria. It works by interfering with the bacterial cell wall synthesis, leading to the destruction of the bacteria. Liferzin is typically used in the treatment of infections like respiratory tract infections, urinary tract infections, and skin infections.
Indications:
Liferzin (Ampicillin Sodium) is indicated for the treatment of infections caused by susceptible organisms. These include:
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Respiratory Infections:
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Pneumonia
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Bronchitis
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Sinusitis
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Pharyngitis and other upper respiratory tract infections.
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Urinary Tract Infections (UTIs):
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Cystitis, pyelonephritis, and other kidney or bladder infections.
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Gastrointestinal Infections:
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Peritonitis
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Enteritis
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Skin and Soft Tissue Infections:
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Wounds, abscesses, or infected burns.
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Meningitis:
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In cases of bacterial meningitis caused by susceptible organisms.
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Endocarditis:
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Infections of the heart's inner lining.
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Other Infections:
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Septicemia (bloodstream infections), osteomyelitis, and certain genital infections.
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Dosages (Usage Instructions):
Liferzin (Ampicillin Sodium) should be administered according to the following guidelines:
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Reconstitution of the Powder:
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To prepare for injection, dissolve the 1g of powder in a suitable diluent such as sterile water for injection or normal saline. The exact volume of diluent will depend on the preferred concentration and the route of administration.
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Intravenous (I.V.) Administration:
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After reconstitution, the solution should be administered slowly via intravenous injection or through an I.V. infusion.
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The typical adult dose for I.V. administration is usually 1-2g every 4-6 hours, depending on the severity of the infection.
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Pediatric dosing will vary depending on the child’s weight and the type of infection being treated.
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Intramuscular (I.M.) Administration:
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If administering intramuscularly, the reconstituted solution can be injected directly into the muscle.
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For most adult infections, 1-2g every 4-6 hours is the usual dosage.
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Duration of Therapy:
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The duration of therapy will depend on the type of infection and the clinical response. Typical courses range from 7 to 14 days, but your healthcare provider will determine the exact length of treatment based on the infection and its response to therapy.
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Side Effects:
Like all medications, Liferzin (Ampicillin Sodium) can cause side effects, though not everyone will experience them. Common and serious side effects may include:
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Common Side Effects:
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Gastrointestinal symptoms such as nausea, vomiting, diarrhea, or abdominal discomfort.
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Rash or hives, often due to an allergic reaction.
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Injection site reactions such as pain, redness, or swelling.
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Serious Side Effects:
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Allergic reactions: Can include symptoms like swelling, difficulty breathing, wheezing, hives, or anaphylaxis (a severe allergic reaction that requires immediate medical attention).
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Severe diarrhea (which may indicate Clostridium difficile infection).
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Liver dysfunction: Symptoms may include yellowing of the skin or eyes (jaundice), dark urine, or abdominal pain.
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Blood disorders: This can include thrombocytopenia (low platelet count), leukopenia (low white blood cell count), or eosinophilia (elevated white blood cells).
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Seizures: Rare but may occur in patients with renal impairment or in those receiving high doses of ampicillin.
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Renal Issues: In cases of kidney problems, dosage adjustments may be necessary to avoid toxicity.
Contraindications:
Liferzin (Ampicillin Sodium) should not be used in the following conditions:
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Hypersensitivity to Penicillins:
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If the patient has a known allergy to ampicillin or any other penicillin antibiotic, the drug should be avoided. Severe allergic reactions, such as anaphylaxis, can occur in sensitive individuals.
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History of Severe Allergic Reactions to Beta-lactams:
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Patients with a history of severe allergic reactions (e.g., rash, swelling, breathing difficulties) to other beta-lactam antibiotics (like cephalosporins) should avoid using Liferzin.
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Severe Renal Impairment:
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In patients with significant renal dysfunction, dose adjustments are necessary, and careful monitoring of renal function is advised during treatment.
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Mononucleosis:
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Ampicillin should be avoided in patients with infectious mononucleosis as it can cause an increased risk of developing a rash.
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Pregnancy and Breastfeeding:
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Although ampicillin is generally considered safe during pregnancy (Category B), it should only be used when clearly needed and prescribed by a healthcare provider.
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It is excreted in breast milk, so breastfeeding mothers should consult a doctor before use.
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Conclusion:
Liferzin (Ampicillin Sodium) 1g Powder for Injection is a broad-spectrum antibiotic that is used for the treatment of a variety of bacterial infections. It is effective against many types of Gram-positive and Gram-negative bacteria and can be administered intravenously or intramuscularly.
The drug should be used under the supervision of a healthcare professional to ensure proper dosing and to monitor for any potential side effects. Allergic reactions to ampicillin, particularly in those with a history of penicillin allergy, should be carefully considered before use. If any severe side effects occur, such as difficulty breathing or severe diarrhea, seek immediate medical attention.
For optimal efficacy and safety, always follow the prescribed dosage and instructions provided by your healthcare provider.
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