Atorvastatin (Atorbet) 10mg Film Coated Tablet 100's

Description:
used to lower high cholesterol levels. Atorvastatin is also used to help reduce the risk of having a heart attack or stroke in people who have high blood pressure and coronary heart disease (CHD) or who are at risk of CHD.

Product Description:

Atorvastatin (Atorbet) 10mg Film-Coated Tablets are a cholesterol-lowering medication from the statin class. Atorvastatin works by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver. This leads to a reduction in low-density lipoprotein (LDL) cholesterol and total cholesterol, while increasing high-density lipoprotein (HDL) cholesterol. It is widely used to reduce the risk of cardiovascular diseases such as heart attack, stroke, and other heart-related complications in patients with high cholesterol levels or existing cardiovascular risk factors.

Each tablet of Atorvastatin (Atorbet) contains 10mg of Atorvastatin and is available in 100 film-coated tablets, designed for easy swallowing.

Key Features:

• Active Ingredient: Atorvastatin 10mg per tablet.

• Formulation: Film-coated tablet for oral administration.

• Mechanism of Action: HMG-CoA reductase inhibitor (Statin). Reduces cholesterol production in the liver and lowers LDL cholesterol.

• Indications: Used to treat high cholesterol (hyperlipidemia), prevent cardiovascular diseases, and manage other cholesterol-related conditions.

• Packaging: Available in 100 tablets per pack.

Indications:

Atorvastatin (Atorbet) 10mg tablets are indicated for:

1. Hyperlipidemia (High Cholesterol):

   • Primary hypercholesterolemia (elevated LDL cholesterol).

   • Mixed dyslipidemia (elevated LDL and triglycerides).

2. Cardiovascular Risk Reduction:

   • Prevention of heart attacks, strokes, and other cardiovascular diseases in patients with high cholesterol, diabetes, or those with a family history of heart disease.

3. Atherosclerosis:

   • Atherosclerotic cardiovascular disease (ASCVD) management, as it reduces the risk of heart attacks and strokes in high-risk patients.

4. Post-Heart Attack Management:

   • Secondary prevention in individuals who have had a heart attack, reducing the risk of future cardiovascular events.

5. Familial Hypercholesterolemia:

   • In cases of genetically inherited high cholesterol.

Dosage:

The dosage of Atorvastatin (Atorbet) 10mg tablets is determined based on the individual patient's cholesterol levels, medical conditions, and risk factors. General dosing guidelines are as follows:

• For Hyperlipidemia (high cholesterol):

  • Initial dose: 10mg to 20mg once daily.

  • Maintenance dose: The dose may be increased to 40mg to 80mg daily if necessary, depending on response and tolerance.

• For Cardiovascular Risk Reduction:

  • Starting dose: 10mg to 20mg once daily.

  • Adjustments are made based on cholesterol levels and the patient’s individual risk.

• For Familial Hypercholesterolemia:

  • Starting doses can vary, but generally, 10mg to 20mg daily are common starting points.

• For Prevention of Cardiovascular Events:

  • The typical starting dose is 10mg, with possible increases based on individual response, up to a maximum of 80mg per day.

Administration:

• Take Atorvastatin (Atorbet) tablets once daily, with or without food.

• Swallow the tablet whole with a glass of water.

• Take the medication at the same time each day to help remember.

Note: Your doctor may adjust the dose based on your cholesterol levels and any other medical conditions you may have.

Side Effects:

Common side effects of Atorvastatin (Atorbet) 10mg tablets include:

• Muscle pain or weakness.

• Digestive problems like nausea, diarrhea, or constipation.

• Headache.

• Stomach discomfort or indigestion.

• Elevated liver enzymes (which may be detected during blood tests).

Serious side effects, though rare, may include:

• Muscle breakdown (rhabdomyolysis), which can cause muscle pain, tenderness, and weakness, and lead to kidney damage. Seek medical attention if you experience severe muscle pain or weakness.

• Liver damage, with symptoms including yellowing of the skin or eyes (jaundice), dark urine, and abdominal pain.

• Memory loss, confusion, or difficulty concentrating.

• Allergic reactions such as rash, itching, swelling of the face or lips, and trouble breathing.

If you experience any of these serious side effects, seek immediate medical help.

Contraindications:

Atorvastatin (Atorbet) 10mg tablets should not be used in the following situations:

1. Hypersensitivity (allergic reactions) to Atorvastatin or any of its ingredients.

2. Active liver disease or unexplained persistent elevations in liver enzymes.

3. Pregnancy: Atorvastatin can harm an unborn baby. Women who are pregnant or planning to become pregnant should not take this medication.

4. Breastfeeding: Atorvastatin is excreted in breast milk, so it should not be used during breastfeeding.

5. Severe renal impairment: Caution should be taken in patients with severe kidney disease, as statins can affect kidney function.

6. Use with strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) without proper medical supervision.

Warnings and Precautions:

• Liver Function: Liver function should be monitored before starting treatment with Atorvastatin and periodically during treatment, as statins can cause liver damage.

• Muscle Problems: Statins, including Atorvastatin, can cause muscle-related issues, from mild pain to more severe conditions like rhabdomyolysis. Patients should report any unexplained muscle pain, tenderness, or weakness to their healthcare provider.

• Diabetes Risk: Statins have been associated with a small increased risk of developing type 2 diabetes.

• Alcohol Use: Limit alcohol consumption, as it can increase the risk of liver damage when taking Atorvastatin.

• Pregnancy and Breastfeeding: Atorvastatin should not be used during pregnancy or while breastfeeding. Women of childbearing age should use effective contraception during treatment.

Drug Interactions:

Atorvastatin (Atorbet) may interact with several medications, including:

• CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, erythromycin) can increase Atorvastatin levels and the risk of side effects.

• Cyclosporine, an immunosuppressive drug, can increase the concentration of Atorvastatin.

• Antifungal medications (e.g., itraconazole), HIV protease inhibitors, or antibiotics like clarithromycin can interfere with Atorvastatin metabolism and increase the risk of side effects.

• Other cholesterol-lowering medications such as gemfibrozil or niacin can increase the risk of muscle problems when taken with Atorvastatin.

• Warfarin (a blood thinner) may interact with Atorvastatin, affecting blood clotting times, so regular monitoring is necessary.

Always inform your healthcare provider of all other medications you are taking, including over-the-counter drugs, supplements, and herbal products.

Storage:

• Store Atorvastatin (Atorbet) tablets at room temperature (15°C to 30°C).

• Keep in a dry place, away from moisture and direct sunlight.

• Keep the tablets out of the reach of children.

Conclusion:

Atorvastatin (Atorbet) 10mg tablets are an effective treatment for lowering LDL cholesterol and reducing the risk of heart-related events. It is commonly prescribed for individuals with high cholesterol or cardiovascular risk factors. However, it should be used with caution in people with liver disease, kidney problems, and muscle disorders. Regular monitoring of liver function and muscle symptoms is essential. Always follow your healthcare provider’s dosage instructions and report any side effects or unusual symptoms promptly.