Atorvastatin (Fredtor) 10mg Film Coated Tablets 100's

Description:

Used to lower high cholesterol levels. Atorvastatin is also used to help reduce the risk of having a heart attack or stroke in people who have high blood pressure and coronary heart disease (CHD) or who are at risk of CHD.

Product Description:

Atorvastatin (Fredtor) 10mg Film-Coated Tablets are a statin-based medication used primarily to lower cholesterol and reduce the risk of heart disease. Atorvastatin works by inhibiting the enzyme HMG-CoA reductase, which plays a critical role in the liver's production of cholesterol. By reducing cholesterol production, Atorvastatin helps lower levels of low-density lipoprotein (LDL) or "bad cholesterol," and total cholesterol, while potentially increasing high-density lipoprotein (HDL) or "good cholesterol."

Each tablet contains 10mg of Atorvastatin and is designed for oral administration. Available in 100 film-coated tablets, this formulation is suitable for both short-term and long-term treatment plans for managing cholesterol and preventing cardiovascular events.

Key Features:

• Active Ingredient: Atorvastatin 10mg per tablet.

• Formulation: Film-coated tablet for easy swallowing.

• Mechanism of Action: HMG-CoA reductase inhibitor (statin)—inhibits cholesterol production in the liver.

• Indications: Used to treat hyperlipidemia (high cholesterol), prevent cardiovascular events, and manage dyslipidemia.

• Packaging: Available in 100 tablets per pack.

Indications:

Atorvastatin (Fredtor) 10mg tablets are indicated for:

1. Hyperlipidemia (High Cholesterol):

   • Treatment of primary hypercholesterolemia (high LDL cholesterol) and mixed dyslipidemia (elevated LDL and triglycerides).

2. Cardiovascular Risk Reduction:

   • Prevention of heart attacks, strokes, and other cardiovascular diseases in patients with elevated cholesterol or a family history of heart disease.

3. Atherosclerosis:

   • Management of atherosclerosis to reduce the risk of cardiovascular events in individuals with existing coronary artery disease (CAD).

4. Post-Heart Attack Management:

   • Used to prevent future heart-related events in patients who have experienced a heart attack or stroke.

5. Familial Hypercholesterolemia:

   • Treatment of genetically inherited high cholesterol conditions.

Dosage:

The dosage of Atorvastatin (Fredtor) 10mg tablets depends on the patient's cholesterol levels, overall health, and response to the medication. The following are general guidelines:

• For Hyperlipidemia:

  • Initial dose: 10mg to 20mg once daily.

  • The dose can be adjusted depending on response, up to a maximum of 80mg per day.

• For Cardiovascular Risk Reduction:

  • Starting dose: 10mg once daily, with the possibility of increasing the dose to 20mg-40mg depending on cholesterol levels and risk factors.

• For Familial Hypercholesterolemia:

  • Starting dose: 10mg daily, with potential dose adjustments depending on response.

Administration:

• Atorvastatin (Fredtor) should be taken once daily at any time of the day, with or without food.

• Swallow the tablet whole with a glass of water; do not crush or chew the tablet.

• It's best to take it at the same time each day to maintain consistency.

• If a dose is missed, take it as soon as you remember unless it's almost time for the next dose. Do not take two doses at the same time.

Side Effects:

Common side effects of Atorvastatin (Fredtor) 10mg tablets include:

• Muscle pain, tenderness, or weakness.

• Digestive issues such as nausea, constipation, diarrhea, or stomach pain.

• Headache.

• Dizziness.

• Insomnia (difficulty sleeping).

More serious side effects (rare) include:

• Muscle breakdown (rhabdomyolysis), which can cause severe muscle pain, weakness, or tenderness and lead to kidney failure.

• Liver damage: Symptoms may include yellowing of the skin or eyes, dark urine, and severe abdominal pain.

• Memory problems or confusion.

• Severe allergic reactions: Rash, itching, swelling of the face or throat, difficulty breathing.

• Kidney problems: Changes in urine output, swelling, or weight gain.

If you experience any of these serious side effects, you should seek immediate medical attention.

Contraindications:

Atorvastatin (Fredtor) 10mg tablets should not be used in the following situations:

1. Hypersensitivity (allergic reaction) to Atorvastatin or any of its ingredients.

2. Active liver disease or unexplained persistent elevations in liver enzymes.

3. Pregnancy: Atorvastatin can harm the unborn baby. It should not be taken during pregnancy.

4. Breastfeeding: Atorvastatin passes into breast milk, so it should not be used during breastfeeding.

5. Severe renal impairment: Caution is advised in patients with severe kidney disease.

6. Patients who are taking strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, clarithromycin) without medical supervision.

Warnings and Precautions:

• Liver Function: Liver enzymes should be monitored before starting treatment and periodically thereafter, as statins can cause liver damage.

• Muscle Problems: Atorvastatin can cause muscle pain or weakness (myopathy). If you experience unexplained muscle pain or tenderness, contact your healthcare provider immediately.

• Diabetes Risk: Statins may increase blood sugar levels, and there is a small risk of developing type 2 diabetes with long-term use.

• Pregnancy and Breastfeeding: Atorvastatin should not be used during pregnancy or breastfeeding due to the potential harm to the baby. Women of childbearing age should use effective contraception.

• Alcohol: Limit alcohol intake, as alcohol can increase the risk of liver damage when combined with statins.

Drug Interactions:

Atorvastatin (Fredtor) may interact with several other medications, including:

• CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, erythromycin) can increase the level of Atorvastatin in the blood and may lead to an increased risk of side effects.

• Cyclosporine: Can increase the concentration of Atorvastatin in the blood.

• Other cholesterol-lowering agents (e.g., gemfibrozil, niacin): Can increase the risk of muscle-related side effects when combined with Atorvastatin.

• Warfarin (a blood thinner): Atorvastatin may alter the effects of warfarin, so regular monitoring is required.

• Digoxin: Combined use of Atorvastatin and digoxin may increase digoxin levels in the blood.

• Antacids: Some antacids may interfere with the absorption of Atorvastatin.

Always inform your healthcare provider about any other medications you are taking, including over-the-counter drugs, supplements, and herbal products.

Storage:

• Store Atorvastatin (Fredtor) tablets at room temperature (15°C to 30°C).

• Keep in a dry place, away from moisture and direct sunlight.

• Keep out of reach of children.

Conclusion:

Atorvastatin (Fredtor) 10mg film-coated tablets are effective in managing high cholesterol and reducing the risk of cardiovascular events like heart attacks and strokes. It is commonly used in patients with high cholesterol, heart disease, and other risk factors. Regular monitoring of liver function and muscle symptoms is important during treatment. Always follow your healthcare provider’s instructions regarding dosage and duration of use, and report any unusual symptoms or side effects promptly.