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Bambang Pharmaceutical Depot Inc.

Azithromycin (Azitobact) 500mg Tablet 3's

Azithromycin (Azitobact) 500mg Tablet 3's

Regular price ₱132.00
Regular price ₱264.00 Sale price ₱132.00
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Product Description:

Azithromycin (Azitobact) 500mg Tablet is an antibiotic medication belonging to the macrolide class of drugs. It is formulated to treat various bacterial infections by inhibiting the growth of bacteria. Azithromycin is known for its broad-spectrum activity against a range of bacteria, including those responsible for respiratory, skin, and soft tissue infections. It is typically available in packs of 3 tablets, with each tablet containing 500mg of azithromycin.

Azithromycin works by binding to bacterial ribosomes, disrupting protein synthesis, and inhibiting bacterial growth. It is effective against a variety of gram-positive, gram-negative, and atypical bacteria. The formulation is commonly used for both adult and pediatric patients and is available in different strengths for tailored dosing.


Indications:

Azithromycin (Azitobact) is indicated for the treatment of a variety of bacterial infections, including:

  1. Respiratory tract infections:

    • Community-acquired pneumonia

    • Acute bronchitis

    • Sinusitis

    • Pharyngitis (sore throat)

    • Tonsillitis

  2. Ear infections:

    • Otitis media (middle ear infection)

  3. Skin and soft tissue infections:

    • Impetigo

    • Cellulitis

    • Folliculitis

  4. Sexually transmitted infections (STIs):

    • Chlamydia (e.g., urethritis, cervicitis)

    • Gonorrhea (often as part of combination therapy)

  5. Other bacterial infections:

    • Helicobacter pylori infection (as part of combination therapy for peptic ulcers)

    • Traveler's diarrhea (due to certain bacteria)

    • Pelvic inflammatory disease (PID)


Dosage and Administration:

The dosage of Azithromycin (Azitobact) depends on the condition being treated, as well as the patient's age and medical history. Below are typical dosage guidelines:

  1. For Adults:

    • Respiratory and soft tissue infections: 500mg on day 1, followed by 250mg daily for 4 more days (total 5-day course).

    • Chlamydia: A single 1g dose.

    • Gonorrhea: Often combined with other antibiotics for dual therapy; typical dosing may involve a single 1g dose of azithromycin.

    • Helicobacter pylori: Used in combination with other medications for peptic ulcer disease (dosage varies based on regimen).

  2. For Children:

    • The pediatric dosing is based on the child's weight and the condition being treated. Typical pediatric doses range from 10mg/kg to 20mg/kg once daily, often for 3 to 5 days.

Administration:

  • Take the tablets with or without food.

  • It is recommended to take the tablet at the same time each day.

  • Swallow the tablet whole; do not chew, crush, or split the tablet.

Important:

  • Complete the entire course of treatment, even if you start feeling better before the medication is finished, to prevent bacterial resistance.


Side Effects:

Common side effects of Azithromycin (Azitobact) include:

Common Side Effects:

  • Diarrhea

  • Nausea or vomiting

  • Abdominal pain or discomfort

  • Headache

  • Dizziness

  • Fatigue

Serious Side Effects:

  • Allergic reactions: Symptoms may include rash, itching, swelling, severe dizziness, or trouble breathing.

  • Liver problems: Yellowing of the skin or eyes (jaundice), dark urine, or abdominal pain.

  • QT interval prolongation: Can cause irregular heartbeats, which may be serious or life-threatening (especially in those with heart disease or on other drugs that affect heart rhythm).

  • Clostridium difficile-associated diarrhea: Severe diarrhea associated with overgrowth of C. difficile bacteria.

  • Hearing loss: Rare, but can occur, especially with high doses or in individuals with preexisting kidney issues.

  • Pancreatitis: Rare, but possible inflammation of the pancreas.


Contraindications:

Azithromycin (Azitobact) should be avoided in the following conditions:

  1. Hypersensitivity: Known allergy to azithromycin or other macrolide antibiotics (such as erythromycin or clarithromycin).

  2. Severe hepatic impairment: Use with caution or avoid in patients with significant liver disease.

  3. History of arrhythmias: Especially QT prolongation or Torsades de pointes, azithromycin should be avoided or used with caution in these patients.

  4. Pregnancy: Azithromycin is classified as Category B in pregnancy, meaning it is generally considered safe but should be used during pregnancy only when clearly needed. Always consult a doctor before use.

  5. Breastfeeding: Azithromycin is excreted in breast milk. Consult a healthcare provider before using if breastfeeding.

  6. Drug interactions: Azithromycin should be used cautiously with certain medications, especially those that can affect the QT interval, such as antiarrhythmic agents (e.g., amiodarone), certain antifungals, and antidepressants.


Precautions:

  • Kidney or Liver Disease: Use with caution in patients with renal or hepatic impairment. Adjustments in dosage may be necessary.

  • Heart Problems: Patients with a history of heart disease or arrhythmias should be monitored closely, as azithromycin may affect heart rhythm.

  • Diarrhea: If severe diarrhea occurs, consider testing for Clostridium difficile and stopping the medication if necessary.

  • Superinfection: Prolonged use of azithromycin can lead to overgrowth of non-susceptible organisms (e.g., fungi, resistant bacteria).


Summary:

Azithromycin (Azitobact) 500mg Tablet is a broad-spectrum antibiotic used to treat a variety of bacterial infections, including respiratory infections, ear infections, sexually transmitted diseases, and skin infections. It is typically dosed as a 5-day course for most indications and is well-tolerated with common side effects such as gastrointestinal discomfort. Serious side effects can occur, including liver toxicity, heart issues (QT prolongation), and severe diarrhea caused by Clostridium difficile.

Always complete the full course of therapy and consult a healthcare provider if side effects occur. Avoid abrupt discontinuation, and never self-medicate or adjust dosage without medical guidance.

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