Candesartan (Giran 16) 16mg Angiotensin 2 Receptor Blocker Tablet 30's

Certainly! Below is the detailed information for Candesartan (Giran 16) 16mg Angiotensin 2 Receptor Blocker Tablet 30's:

Product Description:

Candesartan (Giran 16) 16mg Angiotensin 2 Receptor Blocker Tablet is a medication used primarily to treat high blood pressure (hypertension) and heart failure. The active ingredient in this tablet, Candesartan, is an Angiotensin II Receptor Blocker (ARB). Candesartan works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict, thereby helping to relax the blood vessels. This reduces blood pressure and helps the heart pump more efficiently, making it useful for treating hypertension and heart failure. This formulation contains 16mg of Candesartan and is typically packaged in a 30-tablet bottle.

Indications:

Candesartan (Giran 16) is indicated for the following conditions:

• Hypertension (High Blood Pressure): Candesartan is used to lower high blood pressure, reducing the risk of complications such as stroke, heart attack, and kidney damage.

• Heart Failure: It is used in the treatment of heart failure to improve the function of the heart, alleviate symptoms, and reduce the risk of hospitalization and death due to heart failure.

• Chronic Kidney Disease (in certain patients): Candesartan may be used in patients with kidney disease to protect kidney function, especially if they have high blood pressure or diabetes.

Dosage:

The dosage of Candesartan (Giran 16) will depend on the condition being treated, the patient’s response to the medication, and any coexisting medical conditions. The typical dosages are as follows:

• For Hypertension:

  • Initial Dose: 8mg to 16mg once daily.

  • Maintenance Dose: 16mg to 32mg once daily, depending on the patient’s response and blood pressure control. The maximum recommended dose is 32mg once daily.

• For Heart Failure:

  • Initial Dose: Typically 4mg to 8mg once daily.

  • Maintenance Dose: The dose is gradually increased to 16mg to 32mg once daily, depending on the patient's tolerance and clinical condition.

Important Note: Dosage adjustments may be needed in patients with renal impairment or those who are elderly. Always follow the dosage recommendations provided by a healthcare professional.

Side Effects:

Common side effects of Candesartan (Giran 16) include:

• Dizziness or lightheadedness: Particularly when standing up quickly, due to lowered blood pressure.

• Headache: A common side effect, especially when starting treatment.

• Fatigue or tiredness: Some individuals may feel unusually tired or weak.

• Upper respiratory tract infections: Symptoms may include a sore throat, cough, or nasal congestion.

• Back pain and muscle cramps.

Less common but serious side effects include:

• Low blood pressure (hypotension): This may occur, especially after the first dose or when the dosage is increased.

• Hyperkalemia (high potassium levels): Elevated potassium levels in the blood can be dangerous and cause symptoms like weakness, irregular heartbeat, or numbness.

• Kidney dysfunction: Rarely, Candesartan may affect kidney function, leading to elevated creatinine or blood urea nitrogen (BUN) levels.

• Angioedema (swelling of the face, lips, or throat): This is a serious, rare reaction that requires immediate medical attention.

Severe allergic reactions: Difficulty breathing, swelling of the throat, and hives (urticaria) are rare but serious reactions.

Contraindications:

Candesartan (Giran 16) should not be used in the following conditions:

• Hypersensitivity to Candesartan or any component of the tablet: If you have an allergic reaction to Candesartan or other ARBs, you should avoid this medication.

• Pregnancy: Candesartan is contraindicated during pregnancy, particularly in the second and third trimesters, as it can harm the developing fetus, causing birth defects or fetal death.

• Breastfeeding: Candesartan should not be used during breastfeeding, as it may pass into breast milk and affect the baby.

• Severe Renal Impairment: If a patient has severe kidney problems or is on dialysis, Candesartan should be avoided as it can worsen kidney function.

• Bilateral Renal Artery Stenosis (Narrowing of the Kidney Arteries): Candesartan should not be used in patients with this condition due to the increased risk of kidney failure.

• Severe Hyperkalemia (High Potassium Levels): If the patient has high potassium levels in the blood, Candesartan should not be used as it can exacerbate this condition.

Precautions:

• Renal Impairment: Candesartan should be used with caution in patients with mild to moderate kidney disease. Dosage adjustments may be necessary, and renal function should be monitored regularly.

• Electrolyte Imbalance: Candesartan can affect potassium levels, so patients should have their electrolytes monitored regularly. If the patient is taking other medications that increase potassium levels, extra caution is necessary.

• Hypotension: Careful monitoring of blood pressure is important, especially when initiating treatment or increasing the dose, as Candesartan can cause low blood pressure.

• Liver Impairment: In patients with liver disease, Candesartan should be used cautiously, and the dosage may need to be adjusted.

• Concomitant Use with Other Antihypertensives: If Candesartan is used in combination with other antihypertensive medications (e.g., diuretics, ACE inhibitors), the risk of low blood pressure may increase. Regular monitoring is essential.

Drug Interactions:

• Potassium Supplements and Potassium-Sparing Diuretics: The combination of Candesartan with potassium supplements or potassium-sparing diuretics can increase the risk of hyperkalemia (high potassium levels).

• ACE Inhibitors: When used together with ACE inhibitors, especially in patients with kidney disease or diabetes, there is an increased risk of renal impairment and hyperkalemia.

• Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): NSAIDs may reduce the blood pressure-lowering effects of Candesartan and may increase the risk of kidney problems when taken together.

Summary:

Candesartan (Giran 16) is an Angiotensin II Receptor Blocker (ARB) used for the treatment of hypertension and heart failure. It works by relaxing blood vessels to lower blood pressure and improve heart function. It is available in 16mg tablets and typically taken once daily. It is important to monitor for side effects, especially related to kidney function, potassium levels, and blood pressure. Always consult with a healthcare provider before starting or adjusting the dosage of this medication.

If you need more details or have specific concerns, it's essential to consult a healthcare provider for personalized guidance.