Skip to product information
1 of 1

Bambang Pharmaceutical Depot Inc.

Clindamycin Phospate (Corsin) 300/150mg/ml (300mg/2ml) Solution for Injection (IM/IV)

Clindamycin Phospate (Corsin) 300/150mg/ml (300mg/2ml) Solution for Injection (IM/IV)

Regular price ₱170.00
Regular price ₱340.00 Sale price ₱170.00
Sale Sold out
Tax included. Shipping calculated at checkout.

Certainly! Here's a detailed product description for Clindamycin Phosphate (Corsin) 300/150mg/ml (300mg/2ml) Solution for Injection (IM/IV):


Product Description:

Clindamycin Phosphate (Corsin) is an antibiotic used to treat a variety of bacterial infections. It is available as a solution for injection, containing 300mg of clindamycin phosphate per 2ml (equivalent to 150mg/ml). Clindamycin is a lincosamide antibiotic that works by inhibiting bacterial protein synthesis, thereby preventing bacteria from growing and multiplying. It is commonly used for serious infections caused by susceptible anaerobic and gram-positive bacteria.

Corsin is administered via intravenous (IV) or intramuscular (IM) injection and is typically used when oral therapy is not feasible or when a more immediate effect is required.


Indications:

Clindamycin Phosphate (Corsin) 300/150mg/ml is indicated for the treatment of infections caused by susceptible microorganisms, including:

  1. Soft Tissue Infections:

    • Abscesses, cellulitis, and other skin and soft tissue infections caused by Staphylococcus aureus (including methicillin-resistant Staphylococcus aureus, MRSA) or Streptococcus species.

  2. Respiratory Tract Infections:

    • Severe infections such as pneumonia, lung abscesses, and empyema (pus in the pleural space) caused by susceptible bacteria.

  3. Bone and Joint Infections:

    • Osteomyelitis and septic arthritis, particularly when caused by Staphylococcus aureus or other susceptible organisms.

  4. Intra-Abdominal Infections:

    • Such as peritonitis or abscesses, where anaerobic bacteria are often involved.

  5. Gynecological Infections:

    • For the treatment of conditions like endometritis or pelvic inflammatory disease caused by susceptible bacteria.

  6. Severe Dental Infections:

    • In cases of periodontal infections and dental abscesses caused by anaerobic bacteria.

  7. Septicemia:

    • For the treatment of bloodstream infections caused by susceptible organisms.


Dosage:

The dosage of Clindamycin Phosphate (Corsin) 300/150mg/ml will depend on the type of infection being treated and the patient's clinical condition. The general dosage guidelines are as follows:

  1. For Adults:

    • Severe infections (e.g., pneumonia, soft tissue infections, osteomyelitis):

      • Initial dose: 600mg to 1200mg per day, administered as IV infusion in divided doses every 8-12 hours.

      • Maintenance dose: 600mg to 900mg per day in divided doses, depending on the severity of the infection.

    • Septicemia and severe infections:

      • Initial dose: 1200mg to 1800mg per day, administered via IV injection or infusion.

      • Maintenance dose: After the initial response, the dose can be reduced based on clinical improvement.

    • Soft Tissue and Bone Infections:

      • Dose: 300mg to 600mg, every 6-8 hours via IV or IM injection.

  2. For Pediatric Patients:

    • Dosing for children is based on weight and severity of the infection. Dosage ranges typically range from 20mg/kg/day to 40mg/kg/day, divided into 3-4 doses.

Administration:

  • Intravenous (IV) injection: Administered slowly over at least 10-60 minutes to avoid vein irritation.

  • Intramuscular (IM) injection: Inject deeply into a large muscle, usually in the gluteal region.

The total treatment duration will depend on the type and severity of the infection, typically ranging from 7 to 14 days.


Side Effects:

Like all medications, Clindamycin Phosphate (Corsin) may cause side effects. Some of the most common and serious side effects include:

  1. Common side effects:

    • Gastrointestinal issues: Nausea, vomiting, abdominal pain, diarrhea, and indigestion.

    • Injection site reactions: Pain, redness, or swelling at the site of injection, especially with IM injection.

    • Rash: Skin rash or itching.

  2. Serious side effects:

    • Clostridium difficile-associated diarrhea (CDAD): A serious condition that can result in severe colitis (inflammation of the colon). Symptoms may include watery diarrhea, fever, abdominal cramping, and blood in the stool. This is a known risk of all antibiotics, particularly with clindamycin.

    • Hepatotoxicity: Liver damage, indicated by elevated liver enzymes or jaundice (yellowing of the skin/eyes).

    • Allergic reactions: Rash, itching, swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing (indicative of an anaphylactic reaction).

    • Severe skin reactions: Such as Stevens-Johnson syndrome or toxic epidermal necrolysis (though these are rare).

    • Blood disorders: Low white blood cell count (leukopenia), low red blood cell count (anemia), or low platelet count (thrombocytopenia).

  3. Other possible effects:

    • Headache, dizziness, fatigue, and changes in taste.


Contraindications:

Clindamycin Phosphate (Corsin) 300/150mg/ml is contraindicated in the following situations:

  1. Hypersensitivity:

    • In patients who are allergic to clindamycin or lincomycin or any of the components of the injection.

  2. History of Colitis:

    • Contraindicated in patients with a history of gastrointestinal disease, particularly colitis (including Clostridium difficile-associated diarrhea) or a history of severe gastrointestinal upset with the use of antibiotics.

  3. Severe Liver Disease:

    • Contraindicated in patients with severe hepatic impairment, as the drug is metabolized in the liver and may lead to toxicity.

  4. Pregnancy:

    • Clindamycin is classified as Category B for pregnancy. It is not contraindicated but should be used with caution and only if the benefits outweigh the risks to the fetus. Consultation with a healthcare provider is necessary.

  5. Breastfeeding:

    • Clindamycin passes into breast milk in small amounts. Caution should be used, and it should only be administered if clearly needed, with monitoring for any side effects in the infant.


Precautions:

  1. Gastrointestinal Risks:

    • Clindamycin has been associated with an increased risk of C. difficile-associated diarrhea (CDAD), which can be life-threatening. Patients should be closely monitored for signs of severe gastrointestinal issues (e.g., persistent diarrhea or abdominal cramping).

  2. Renal and Hepatic Function:

    • Renal function should be monitored in patients with kidney impairment.

    • Liver function should also be assessed, particularly in long-term treatment or patients with pre-existing liver disease.

  3. Antibiotic Resistance:

    • As with all antibiotics, there is a risk of antibiotic resistance. It is important that Clindamycin be used only for infections that are proven or strongly suspected to be susceptible to it.

  4. Use in Infants and Children:

    • In pediatric patients, dosage adjustments are necessary, and special care should be taken in younger children, particularly for infections such as respiratory infections.

  5. Injection Site Reactions:

    • There may be pain, redness, or swelling at the IM injection site, especially with large doses or repeated injections. To reduce discomfort, injection should be administered into large muscle groups.


Summary:

Clindamycin Phosphate (Corsin) 300/150mg/ml is an antibiotic used to treat a range of bacterial infections, including soft tissue infections, respiratory infections, bone infections, and septicemia. It works by inhibiting bacterial protein synthesis and is administered via IV or IM injection.

The typical dosage for adults is 600mg to 1200mg per day, depending on the severity of the infection. Side effects can include gastrointestinal upset, rash, and more serious effects like Clostridium difficile diarrhea or liver damage.

Contraindications include hypersensitivity, history of colitis, and severe liver disease. It should be used with caution in pregnant or breastfeeding women and individuals with pre-existing gastrointestinal or liver conditions.

As with all antibiotics, Clindamycin should be used under the supervision of a healthcare professional to ensure safe and effective treatment.

View full details

Product Features

Highlights

Details

Lot #

Expiry Date

"For All Your Pharma And Medical Supply Needs"

  • MEDICINES

    We offer large range of generics and branded tablets, capsules, topicals, suppositories, drops or suspensions, inhalers and injections.

  • SUPPLEMENTS

    High quality yet very affordable vitamins and minerals, specialty supplements, herbals and botanicals, sports nutrition, and weight management.

  • MEDICAL SUPPLIES

    We serve all types of medical supplies needed in clinics, laboratories, and hospitals like cottons, gauze, alcohol, swabs, gloves, bandages, lancets, glucometer, etc.

  • MEDICAL EQUIPMENT

    We also serve durable and affordable medical devices and equipment needed in clinics, laboratories and hospitals.

1 of 4