Co Amoxiclav (Meoxiclav DS) 457mg/5ml Powder for Oral Suspension 70ml

Antibacterial

For the treatment of the following infections caused by susceptible microorganisms: Upper respiratory tract infections (including ENT infections): Tonsillitis, sinusitis, otitis media. Lower respiratory tract infections: Acute and chronic bronchitis, pneumonia, lung abscess.

Certainly! Here's a detailed breakdown for Co-Amoxiclav (Meoxiclav DS) 457mg/5ml Powder for Oral Suspension 70ml:

Product Description:

Co-Amoxiclav (Meoxiclav DS) 457mg/5ml Powder for Oral Suspension 70ml is a broad-spectrum antibiotic combination containing Amoxicillin (a penicillin-type antibiotic) and Clavulanic Acid. The combination is designed to extend the effectiveness of Amoxicillin by inhibiting the beta-lactamase enzymes produced by certain bacteria that would otherwise make Amoxicillin ineffective.

Each 5ml of the oral suspension contains 457 mg of Co-Amoxiclav, which consists of 400 mg of Amoxicillin and 57 mg of Clavulanic Acid. The medication comes in a 70 ml bottle of powder, which, once reconstituted with water, provides an oral suspension for easy dosing.

Indications:

Co-Amoxiclav (Meoxiclav DS) is indicated for the treatment of infections caused by bacteria that are susceptible to this combination. These include:

1. Respiratory Tract Infections:

   • Acute and chronic bronchitis

   • Pneumonia

   • Sinusitis

   • Otitis media (middle ear infection)

2. Urinary Tract Infections (UTIs):

   • Cystitis

   • Pyelonephritis

3. Skin and Soft Tissue Infections:

   • Cellulitis

   • Abscesses

   • Wounds or burns

4. Bone and Joint Infections:

   • Infections involving bones and joints that are susceptible to bacterial infections.

5. Dental Infections:

   • Infections after dental procedures or infections like periodontal abscesses.

6. Intra-abdominal Infections:

   • Peritonitis

   • Infected biliary tract infections

7. Prophylaxis:

   • It may also be used as prophylaxis for infections during surgical procedures.

Dosages:

The dosage of Co-Amoxiclav (Meoxiclav DS) will depend on the patient's age, weight, the type of infection, and the severity of the condition. Below are general dosing guidelines for Co-Amoxiclav oral suspension:

For Adults and Children Over 12 Years:

• The usual dose for most infections is 10 ml (914 mg), which contains 800 mg of Amoxicillin and 114 mg of Clavulanic Acid, taken every 12 hours.

• In severe infections, the dose may be increased to 12.5 ml (1142.5 mg), taken every 12 hours.

• The maximum dose should not exceed 6,000 mg of Amoxicillin and 864 mg of Clavulanic Acid per day.

For Children (age 2-12 years):

• Mild to moderate infections: The dose is typically 5 ml (457 mg), taken every 12 hours.

• For severe infections, the dose may be increased according to the child’s weight.

• Children under 2 years: The dose should be adjusted carefully based on the child’s weight.

Important: Always follow the specific dosage instructions given by your doctor, as they may adjust the dose based on individual needs or the severity of the infection.

Side Effects:

As with all medications, Co-Amoxiclav (Meoxiclav DS) can cause side effects, although not everyone will experience them. Some of the common and serious side effects include:

Common Side Effects:

• Gastrointestinal issues:

  • Diarrhea

  • Nausea and vomiting

  • Indigestion or stomach discomfort

  • Oral or vaginal thrush (fungal infection)

• Skin rash or itching

Serious Side Effects:

• Allergic reactions: Symptoms such as swelling of the face, lips, or throat, difficulty breathing, and hives. If any of these symptoms occur, seek emergency medical attention immediately.

• Liver problems: Signs include yellowing of the skin or eyes (jaundice), dark urine, and abdominal pain.

• Severe diarrhea (pseudomembranous colitis): A serious infection of the colon that may be associated with the use of antibiotics.

• Blood disorders: Symptoms such as unusual bruising, bleeding, or fatigue. This could indicate a problem with blood cell production.

• Severe skin reactions: Such as blistering, peeling, or red skin. Rare but severe reactions may occur.

• Kidney problems: Decreased urine output, swelling, or fatigue.

If any serious side effects are observed, seek medical help immediately.

Contraindications:

Co-Amoxiclav (Meoxiclav DS) should not be used in the following situations:

1. Hypersensitivity (allergy) to Amoxicillin, Clavulanic Acid, or any other components of the formulation.

2. History of severe allergic reactions to penicillins or other beta-lactam antibiotics (e.g., cephalosporins).

3. Liver dysfunction or a history of jaundice associated with the use of Amoxicillin/Clavulanic Acid combinations.

4. Mononucleosis (infectious mononucleosis): Patients with this condition may be at increased risk for developing a rash when treated with Amoxicillin.

5. Renal (kidney) impairment: Caution is required for patients with kidney disease, and the dosage may need to be adjusted.

Precautions:

• Diabetes: Co-Amoxiclav may interfere with some urine glucose tests, so alternate testing methods may be necessary.

• Pregnancy and breastfeeding: Co-Amoxiclav is generally considered safe during pregnancy and breastfeeding, but it should only be used when prescribed by a doctor. It should be used with caution, and only if the benefits outweigh the risks.

• Use in elderly patients: Elderly individuals may be more susceptible to side effects like kidney problems, and dosage adjustments may be necessary in these patients.

Important Notes:

• Completion of the full course: It is essential to finish the entire prescribed course of Co-Amoxiclav (Meoxiclav DS), even if you feel better. Stopping the medication prematurely may lead to the return of the infection.

• Monitor for side effects: Watch for signs of liver or kidney issues, as well as allergic reactions. If you experience any unusual symptoms, inform your doctor.

• Hydration: Drink plenty of fluids, especially if you experience diarrhea, to help prevent dehydration.

Conclusion:

Co-Amoxiclav (Meoxiclav DS) 457mg/5ml Powder for Oral Suspension 70ml is a broad-spectrum antibiotic that is effective for treating a variety of bacterial infections. As with any medication, it is crucial to follow the prescribed dosage and course of treatment, as well as monitor for any adverse effects. Always consult your healthcare provider for personalized advice and adjustments, especially in cases of kidney disease or other underlying health conditions.