Dobutamine 12.50mg/ml (250mg/20ml) Solution For Injection 20ml

1. Heart Failure:

   • Dobutamine is used in the management of acute heart failure or severe chronic heart failure when the heart's pumping ability is compromised. It helps to increase cardiac output (the amount of blood pumped by the heart per minute) by stimulating beta-1 adrenergic receptors on the heart muscle.

2. Cardiac Stress Testing:

   • Dobutamine can be used in diagnostic cardiac stress testing, particularly in patients who cannot perform physical exercise or when pharmacologic stress testing is indicated to evaluate coronary artery disease.

Dobutamine works by mimicking the action of adrenaline (epinephrine) but with a more specific effect on beta-1 adrenergic receptors of the heart. This stimulation increases the force of contraction of the heart muscle (inotropic effect), leading to an increase in cardiac output. It also dilates blood vessels in the kidneys, leading to an increase in renal blood flow.

Usage Instructions:

• Dosage: The dosage of Dobutamine varies depending on the patient's condition and response to the medication. It is typically administered intravenously (IV) under medical supervision.
• Administration: Dobutamine solution should be diluted appropriately according to the specific instructions provided by healthcare providers. It is infused slowly to achieve the desired effect on cardiac output without causing excessive increases in heart rate or blood pressure.
• Monitoring: Patients receiving Dobutamine should be closely monitored for changes in heart rate, blood pressure, and cardiac function to adjust the dosage as necessary and to detect any adverse effects promptly.

Before using Dobutamine, healthcare providers will assess the patient's cardiovascular status and other relevant factors to determine the appropriateness of treatment and the correct dosage regimen. It is essential to follow medical advice and instructions carefully during the administration of Dobutamine.