Furosemide (Edecar) 10mg/ml Solution for Injection (IV/IM) 10 Ampoules x 2ml

Here is the detailed information for Furosemide (Edecar) 10mg/ml Solution for Injection (IV/IM) 10 Ampoules x 2ml:

Product Description:

Furosemide (Edecar) is a loop diuretic medication available as a 10mg/ml solution for injection. Each ampoule contains 2ml, providing a total of 20mg of Furosemide. It is primarily used for its diuretic effect to treat conditions associated with fluid retention and edema. It is administered intravenously (IV) or intramuscularly (IM) under medical supervision. Furosemide (Edecar) is designed to help reduce excess fluid buildup in the body, thereby relieving symptoms such as swelling, shortness of breath, and hypertension.

Indications:

Furosemide (Edecar) is used to treat various medical conditions that involve fluid retention or edema, including:

1. Edema (fluid retention) associated with:

   • Congestive heart failure (CHF).

   • Chronic kidney disease or renal failure.

   • Liver cirrhosis.

   • Nephrotic syndrome (a kidney disorder).

   • Pulmonary edema (fluid accumulation in the lungs, often due to heart failure).

2. Hypertension (high blood pressure), particularly in cases where fluid retention contributes to the condition.

It is typically administered when oral diuretics are not effective or when rapid fluid removal is necessary.

Dosage and Administration:

The dose of Furosemide (Edecar) depends on the patient's condition, response to treatment, and other individual factors. Below are general dosing guidelines:

For Edema:

• Initial Dose: 20 to 40mg IV or IM for adults. The dose can be increased depending on the response, usually in increments of 20 to 40mg.

• Maintenance Dose: Typically ranges from 20mg to 120mg per day, depending on the patient's condition and response.

For Hypertension:

• The typical dose for managing hypertension is 10 to 40mg IV or IM. This may be adjusted based on the patient's blood pressure levels and response to the medication.

For Pediatric Patients:

• The pediatric dose is typically 0.5 to 1mg per kilogram of body weight for initial treatment, administered either IV or IM. The exact dose should be determined by a healthcare provider.

Side Effects:

As with any medication, Furosemide (Edecar) may cause side effects. Not all patients will experience these, but they can include:

Common Side Effects:

• Electrolyte imbalances (e.g., low potassium, sodium, and calcium levels).

• Dehydration (excessive fluid loss).

• Hypotension (low blood pressure), particularly when standing up.

• Dizziness or lightheadedness.

• Headache.

• Nausea or vomiting.

• Increased urination.

Serious Side Effects (Seek immediate medical attention):

• Severe electrolyte imbalances (can cause arrhythmias or muscle weakness).

• Severe dehydration, resulting in dizziness, dry mouth, excessive thirst, and weakness.

• Hearing loss (rare but can occur, particularly with rapid IV administration or high doses).

• Severe hypotension, which may lead to fainting or shock.

• Pancreatitis (inflammation of the pancreas), indicated by severe abdominal pain.

• Kidney damage or acute renal failure.

• Severe allergic reactions (rash, itching, swelling, difficulty breathing).

Contraindications:

Furosemide (Edecar) should not be used in the following situations:

1. Hypersensitivity:

   • Contraindicated in individuals with a known allergy to Furosemide, sulfonamides, or any components of the formulation.

2. Anuria:

   • Furosemide should not be administered to patients with anuria (the inability to produce urine), as it requires kidney function to be effective.

3. Severe Electrolyte Imbalances:

   • Should be avoided in patients with severe hypokalemia, hyponatremia, or other significant electrolyte imbalances unless they are corrected prior to treatment.

4. Severe Liver Disease:

   • Caution is advised in patients with severe liver disease, especially if they have an associated hepatic coma or pre-comatose states.

5. Pregnancy:

   • Furosemide (Edecar) should only be used during pregnancy if absolutely necessary and prescribed by a healthcare provider. It is classified as a Category C drug (risk cannot be ruled out).

6. Breastfeeding:

   • Furosemide is excreted in breast milk, and its use should be avoided unless deemed necessary by a doctor during lactation.

7. Hypovolemia:

   • Furosemide should not be used in patients who are hypovolemic (have low blood volume), as it can worsen fluid loss and cause complications.

8. Children:

   • Use in children should be carefully considered, and doses should be adjusted based on the child's weight and clinical condition.

Precautions:

1. Electrolyte Monitoring:

   • Patients receiving Furosemide (Edecar) should be monitored for electrolyte imbalances, especially low levels of potassium, sodium, and calcium. Regular blood tests are recommended during treatment.

2. Renal Function:

   • Caution is required in patients with renal impairment (kidney disease) as Furosemide may worsen kidney function, especially with prolonged use.

3. Cardiovascular Monitoring:

   • Furosemide can cause a significant drop in blood pressure, so careful monitoring of blood pressure is necessary, particularly in patients with existing hypotension.

4. Hearing Function:

   • High doses or rapid intravenous infusion can increase the risk of ototoxicity (hearing damage), particularly in patients with existing kidney impairment or those receiving other ototoxic drugs.

5. Diabetes:

   • Furosemide may alter glucose tolerance, and diabetic patients should be closely monitored for changes in blood sugar levels.

Summary:

Furosemide (Edecar) 10mg/ml Solution for Injection is a potent loop diuretic used primarily to treat edema associated with heart failure, kidney disease, liver cirrhosis, and other conditions. It is also used in the management of hypertension. The typical adult dose ranges from 20mg to 120mg per day and should be administered under the guidance of a healthcare professional.

• Common Side Effects: Electrolyte imbalances, dizziness, headache, dehydration, and increased urination.

• Serious Side Effects: Severe electrolyte disturbances, dehydration, kidney damage, hearing loss, and allergic reactions.

• Contraindications: Hypersensitivity to Furosemide, anuria, severe electrolyte imbalances, and severe liver disease.

• Precautions: Close monitoring of electrolytes, kidney function, and blood pressure during treatment.

Always use Furosemide as directed by a healthcare provider, and inform them of any pre-existing medical conditions or other medications you are taking.