Generic Name: MAGNESIUM SULFATE

Brand Name: EUROMED

Strength: 250mg/mL (25%)

Form: IM/IV

Manufacturer: 

Imported and Distributed by: 

Classification: 

Indication/Uses: 

1. Eclampsia and Preeclampsia

   • Usage: Magnesium sulfate is indicated for the prevention and treatment of seizures associated with severe preeclampsia and eclampsia.
   • Importance: It helps to prevent and control seizures in pregnant women with these conditions.

2. Hypomagnesemia

   • Usage: Indicated for the treatment of acute hypomagnesemia (low levels of magnesium in the blood).
   • Importance: Correcting magnesium deficiency is crucial as it can lead to symptoms like muscle weakness, seizures, and arrhythmias.

3. Torsades de Pointes

   • Usage: Used in the management of certain types of cardiac arrhythmias, particularly Torsades de Pointes.
   • Importance: It helps stabilize heart rhythm in patients with this specific type of ventricular tachycardia.

4. Asthma Exacerbations

   • Usage: Employed as an adjunct treatment in severe acute asthma exacerbations not responding to conventional therapy.
   • Importance: It can help relax bronchial muscles and improve airflow in severe asthma cases.

5. Neuroprotection in Preterm Labor

   • Usage: Used for neuroprotection of the fetus in preterm labor, typically administered to women at risk of preterm birth before 32 weeks of gestation.
   • Importance: It can reduce the risk of cerebral palsy and other neurologic complications in preterm infants.

Uses

1. Administration Methods

   • Intravenous (IV): For rapid administration in acute settings, such as controlling seizures or treating severe hypomagnesemia.
   • Intramuscular (IM): Can be used when IV access is not available or practical.

2. Mechanism of Action

   • Action: Magnesium sulfate acts as a central nervous system depressant and a calcium antagonist, which helps in stabilizing excitable membranes.
   • Benefit: This results in seizure control, muscle relaxation, and stabilization of cardiac and respiratory functions.

3. Emergency Medicine

   • Usage: Frequently used in emergency settings for immediate effect.
   • Benefit: Provides rapid intervention in life-threatening conditions such as eclampsia and severe asthma.