Product Name: Mefenamic Acid (Mefesaph) 500mg Non-Steroidal Tablet 100's

Product Description:

Mefenamic Acid (Mefesaph) 500mg is a non-steroidal anti-inflammatory drug (NSAID) used primarily for the relief of pain and inflammation. It works by inhibiting the production of prostaglandins, chemicals in the body responsible for inflammation, pain, and fever. This medication is commonly used to treat conditions such as pain from muscle aches, menstrual cramps, arthritis, and minor injuries. It is available in tablet form, making it easy to administer and suitable for adults and children (above a certain age) when prescribed by a doctor.

Indications:

Mefenamic Acid (Mefesaph) 500mg is typically prescribed for:

• Pain relief: For mild to moderate pain such as headaches, toothaches, muscle aches, and back pain.

• Dysmenorrhea (menstrual cramps): To alleviate pain associated with menstruation.

• Osteoarthritis and rheumatoid arthritis: To reduce pain and inflammation in the joints.

• Post-operative pain: For pain following surgery or injury.

• Fever: It can also be used to reduce fever associated with various infections.

Dosage:

The recommended dosage of Mefenamic Acid (Mefesaph) 500mg may vary depending on the condition being treated. Always follow the instructions of a healthcare provider, but typical dosages are as follows:

• Adults:

  • Initial dose: 500 mg (1 tablet) taken orally, followed by 250 mg every 6 hours as needed for pain or inflammation.

  • Maximum dose: Do not exceed 1,000 mg per day.

• For Dysmenorrhea (Menstrual Cramps):

  • Initial dose: 500 mg (1 tablet) at the onset of pain, followed by 250 mg every 6 hours as needed for up to 3 days.

• For Children (12 years and older):

  • Typically, a dose of 250-500 mg per day, as prescribed by a healthcare provider.

• Elderly Patients: Dosage may need to be adjusted, especially if there are concerns about kidney or liver function.

It is recommended to take the medication with food or milk to minimize gastrointestinal irritation.

Side Effects:

Common side effects of Mefenamic Acid (Mefesaph) 500mg include:

• Gastrointestinal issues: Nausea, vomiting, indigestion, stomach pain, diarrhea, or constipation.

• Headaches or dizziness.

• Drowsiness or fatigue.

• Rashes or skin irritation.

• Tinnitus (ringing in the ears), particularly with higher doses or prolonged use.

• Fluid retention or swelling in the legs or feet.

Serious side effects (though rare) include:

• Gastrointestinal bleeding or ulcers: Mefenamic Acid may increase the risk of gastrointestinal bleeding, ulceration, and perforation, especially with prolonged use.

• Kidney problems: Symptoms include reduced urine output, swelling, or weight gain.

• Liver issues: Jaundice (yellowing of the skin/eyes), dark urine, or abdominal pain.

• Severe allergic reactions: Difficulty breathing, swelling of the face or throat, or severe rash.

If any of these serious side effects occur, immediately seek medical attention.

Contraindications:

Mefenamic Acid (Mefesaph) 500mg should not be used in the following situations:

• Allergy to NSAIDs or aspirin: If you have had an allergic reaction to Mefenamic Acid, aspirin, or other NSAIDs in the past, you should not use this medication.

• Active gastrointestinal bleeding or history of peptic ulcers or gastrointestinal disorders (e.g., Crohn's disease, ulcerative colitis).

• Severe liver or kidney disease: Mefenamic Acid can worsen pre-existing liver or kidney issues.

• Pregnancy: Mefenamic Acid is generally contraindicated during pregnancy, especially in the third trimester, as it may harm the fetus or interfere with labor. It should be avoided unless prescribed by a doctor.

• Breastfeeding: It should be used cautiously while breastfeeding, and only if the potential benefits outweigh the risks.

• Children under 12 years of age: The use of Mefenamic Acid in children under 12 years old is generally not recommended unless prescribed by a doctor.

• Heart problems: Mefenamic Acid can increase the risk of cardiovascular events, including heart attack and stroke, particularly with prolonged use or in individuals with pre-existing heart conditions.

Warnings and Precautions:

• Long-term use: Extended use of Mefenamic Acid can increase the risk of heart attack, stroke, and gastrointestinal issues such as bleeding or ulcers.

• Interaction with other medications: Mefenamic Acid may interact with blood thinners (like warfarin), diuretics, blood pressure medications, or other NSAIDs, so it is important to inform your healthcare provider of all medications you're currently taking.

Conclusion:

Mefenamic Acid (Mefesaph) 500mg is a potent NSAID that can effectively relieve pain and inflammation when used appropriately. However, like all NSAIDs, it carries the potential for serious side effects, particularly with long-term use. It is essential to follow the prescribed dosage and consult with a healthcare provider before starting treatment, especially if you have any underlying health conditions or are taking other medications. Always take Mefenamic Acid with food to minimize gastrointestinal irritation, and monitor for any unusual symptoms or side effects.