Generic Name: Metrodinazole

Brand Name: Ambidazol

Strength: 125mg / 5ml

Form: Suspension

Manufacturer:

Imported and Distributed by:

Classification: Antiprotozal

Indication/Uses:

Metronidazole (Ambidazol) 125mg/5ml Suspension 60ml is an antimicrobial medication used to treat various infections caused by anaerobic bacteria and protozoa. Here are the primary indications and uses for this suspension:

Indications and Uses

1. Amoebiasis:

   • Intestinal and Extraintestinal Infections: Used to treat amoebic dysentery and liver abscesses caused by Entamoeba histolytica.

2. Giardiasis:

   • Treatment of Giardiasis: Effective against Giardia lamblia infections, which cause gastrointestinal symptoms like diarrhea and abdominal pain.

3. Trichomoniasis:

   • Urogenital Infections: Used to treat infections caused by Trichomonas vaginalis, typically in the urogenital tract.

4. Anaerobic Bacterial Infections:

   • Intra-abdominal Infections: Treats infections such as peritonitis, abscesses, and postoperative wound infections caused by anaerobic bacteria.
   • Dental Infections: Effective for dental infections and acute ulcerative gingivitis (ANUG).
   • Skin and Soft Tissue Infections: Treats anaerobic bacterial infections in skin and soft tissues.

5. Bacterial Vaginosis:

   • Vaginal Infections: Used to treat bacterial vaginosis caused by Gardnerella vaginalis.

6. Helicobacter pylori Infection:

   • Part of Combination Therapy: Sometimes used as part of a combination therapy to treat Helicobacter pylori infections associated with peptic ulcers.

Dosage and Administration

• Dosage: The dosage depends on the specific infection being treated and the age/weight of the patient. For children, the typical dose is based on body weight, commonly ranging from 30 to 50 mg/kg/day, divided into three doses.
• Administration: The suspension should be measured using the provided dosing device and taken orally. It is often taken with food to minimize gastrointestinal discomfort.

Precautions

• Alcohol Consumption: Patients should avoid alcohol during treatment and for at least 48 hours after the last dose due to the risk of a disulfiram-like reaction (nausea, vomiting, flushing).
• Liver Function: Use with caution in patients with severe liver impairment, as metronidazole is metabolized by the liver.
• Central Nervous System: Caution is advised in patients with central nervous system diseases due to potential neurological side effects.

Side Effects

• Common: Possible side effects include nausea, vomiting, diarrhea, and a metallic taste in the mouth.
• Serious: Rare but serious side effects include seizures, peripheral neuropathy (tingling or numbness in the extremities), and severe allergic reactions. Any signs of serious side effects should be promptly reported to a healthcare provider.

Monitoring

• Effectiveness: Monitor the patient's response to treatment, ensuring that the infection symptoms are resolving.
• Adverse Effects: Watch for any signs of serious adverse effects, particularly neurological symptoms, and adjust treatment as necessary.

Metronidazole (Ambidazol) 125mg/5ml Suspension 60ml is used for treating various protozoal and anaerobic bacterial infections. Proper dosing, adherence to treatment guidelines, and monitoring for side effects are essential for effective and safe use of this medication.