Phenylpropanolamine Hydrochloride Chlorphenamine Maleate Paracetamol (Symdex) 6.25mg/500mcg/100mg per ml Drops 15ml

6.25mg/500mcg/100mg per 5ml Syrup

DECONGESTANT / ANTIHISTAMINE / ANALGESIC / ANTIPYRETIC

Here is a detailed overview of Phenylpropanolamine Hydrochloride, Chlorphenamine Maleate, and Paracetamol (Symdex) 6.25mg/500mcg/100mg per ml Drops 15ml:

Product Description:

Symdex is a combination oral drop formulation containing Phenylpropanolamine Hydrochloride (6.25mg), Chlorphenamine Maleate (500mcg), and Paracetamol (100mg) per milliliter. This combination of ingredients is designed to treat symptoms associated with common colds, allergic rhinitis, and flu-like symptoms, including nasal congestion, sneezing, and fever.

• Phenylpropanolamine is a sympathomimetic that works as a decongestant, relieving nasal congestion by constricting blood vessels in the nasal passages.

• Chlorphenamine Maleate is an antihistamine that helps to reduce allergic symptoms such as sneezing, itching, and runny nose by blocking the effects of histamine.

• Paracetamol (also known as acetaminophen) is an analgesic and antipyretic, helping to relieve pain and reduce fever.

This 15ml bottle is designed for easy administration and is used to alleviate symptoms associated with colds, flu, and allergies in both adults and children as directed by a healthcare provider.

Indications:

Symdex is indicated for the relief of symptoms associated with:

• Common cold and flu-like symptoms (fever, sore throat, muscle aches, headache).

• Allergic rhinitis (seasonal or perennial allergies), such as hay fever, with symptoms like sneezing, runny nose, and itching.

• Sinus congestion and nasal stuffiness caused by upper respiratory infections.

• Headaches, fever, and muscle aches often associated with flu or cold.

Dosage:

The dosage of Symdex will vary based on the age of the patient and the severity of the symptoms. It is important to follow the instructions on the product packaging or as directed by a healthcare provider.

For Adults and Children Over 12 Years:

• Dose: 1-2 ml (equivalent to 6.25mg of Phenylpropanolamine, 500mcg of Chlorphenamine Maleate, and 100mg of Paracetamol) every 4-6 hours as needed.

• Maximum dose: Do not exceed 8 ml (equivalent to 50mg of Phenylpropanolamine, 4mg of Chlorphenamine Maleate, and 800mg of Paracetamol) in 24 hours.

For Children (6-12 years):

• Dose: 0.5-1 ml (equivalent to 3.125mg of Phenylpropanolamine, 250mcg of Chlorphenamine Maleate, and 50mg of Paracetamol) every 4-6 hours.

• Maximum dose: Do not exceed 4 ml in 24 hours.

For Children Under 6 Years:

• Use with caution, and only under the guidance of a healthcare provider. Dosing for young children is typically lower and should be determined by a healthcare professional.

Note: Always measure the dose using the provided dropper to ensure accurate administration.

Side Effects:

While Symdex is effective for relieving cold, allergy, and flu symptoms, some patients may experience side effects. These may include:

Common Side Effects:

• Drowsiness, dizziness, or sedation (due to Chlorphenamine Maleate, an antihistamine).

• Dry mouth or throat irritation.

• Gastrointestinal issues such as nausea, vomiting, or stomach upset.

• Restlessness or insomnia (due to Phenylpropanolamine).

Serious Side Effects:

• Allergic reactions, including skin rash, swelling, or difficulty breathing (especially with Chlorphenamine Maleate, which may cause hypersensitivity reactions).

• Elevated blood pressure (due to Phenylpropanolamine, especially with prolonged or excessive use).

• Severe dizziness or fainting (may be related to blood pressure changes).

• Liver damage: Symptoms like yellowing of the skin or eyes (jaundice) can occur, especially with overdose or prolonged high doses of Paracetamol.

• Severe drowsiness or confusion.

Note: If any of these side effects occur, discontinue use and seek medical advice immediately.

Contraindications:

Symdex should not be used in the following situations:

• Hypersensitivity: Known allergy to Phenylpropanolamine, Chlorphenamine Maleate, Paracetamol, or any of the other ingredients in the product.

• Severe hypertension: Phenylpropanolamine can increase blood pressure, and should not be used in individuals with uncontrolled high blood pressure.

• Hyperthyroidism: Patients with thyroid disorders should avoid this product, as Phenylpropanolamine may exacerbate symptoms of hyperthyroidism.

• Glaucoma: Antihistamines like Chlorphenamine Maleate can increase intraocular pressure and should be avoided in individuals with glaucoma.

• Severe liver disease: As Paracetamol is metabolized by the liver, it should be avoided in patients with severe liver impairment, as overdose or prolonged use can cause liver damage.

• Severe renal disease: Caution is required in patients with kidney dysfunction, as Paracetamol may accumulate in the body.

Pregnancy and Breastfeeding:

• Pregnancy: Symdex should be used during pregnancy only if absolutely necessary and prescribed by a doctor. Some ingredients, such as Chlorphenamine Maleate and Phenylpropanolamine, should be used with caution during pregnancy.

• Breastfeeding: Chlorphenamine Maleate may pass into breast milk and cause drowsiness or other adverse effects in the infant. It is generally recommended to avoid use while breastfeeding unless directed by a healthcare provider.

Precautions:

• Alcohol: Avoid alcohol while using this product, as it may increase the sedative effects of Chlorphenamine Maleate and Phenylpropanolamine, leading to increased drowsiness or dizziness.

• Other medications: If you are taking other medications, particularly other decongestants, antihistamines, or antidepressants, consult a healthcare provider to avoid potential drug interactions.

• Chronic conditions: Individuals with heart disease, diabetes, prostate problems, or glaucoma should use this product with caution and under medical supervision.

• Driving and operating machinery: Due to the sedative effect of Chlorphenamine, this product may impair your ability to drive or operate heavy machinery. Use caution until you know how it affects you.

Note: Always follow the prescribed dosage instructions and consult a healthcare provider if you have any questions or concerns regarding the use of Symdex. Avoid prolonged use, and seek medical advice if symptoms persist.