Pregabalin (Convult) 75mg Anti Epileptic Capsule 10's

Here is the detailed product information for Pregabalin (Convult) 75mg Anti-Epileptic Capsule 10's:

Product Description:

Pregabalin (Convult) 75mg is an anti-epileptic medication primarily used for the treatment of epilepsy, neuropathic pain, and generalized anxiety disorder. It is available in capsule form, with each capsule containing 75mg of pregabalin. Pregabalin works by affecting the way nerves send messages to the brain, helping to reduce the occurrence of seizures, manage pain associated with nerve damage, and alleviate symptoms of anxiety.

Pregabalin is also used to treat conditions such as fibromyalgia and restless legs syndrome (RLS). It is thought to work by inhibiting certain calcium channels in nerve cells, which helps to stabilize electrical activity in the brain and reduce nerve excitability.

Indications:

Pregabalin (Convult) 75mg is indicated for the following conditions:

1. Epilepsy:

   • Adjunctive treatment for partial seizures with or without secondary generalization in adults.

2. Neuropathic Pain:

   • Diabetic neuropathy: Pain caused by nerve damage in people with diabetes.

   • Post-herpetic neuralgia: Pain following shingles.

   • Spinal cord injury-related pain.

3. Generalized Anxiety Disorder (GAD):

   • For the management of generalized anxiety disorder in adults.

4. Fibromyalgia:

   • Used for pain management in patients with fibromyalgia, a condition characterized by widespread muscle pain and fatigue.

5. Restless Legs Syndrome (RLS):

   • Pregabalin may be prescribed for the management of symptoms of restless legs syndrome (RLS), a condition causing discomfort and an uncontrollable urge to move the legs.

Dosage:

The dosage of Pregabalin (Convult) 75mg depends on the condition being treated. The usual adult dosing is as follows:

1. Epilepsy (Partial Seizures):

   • Starting dose: 150mg per day, divided into 2 or 3 doses.

   • Maintenance dose: 150mg to 600mg per day, depending on individual response and tolerability. The dose can be increased gradually.

   • Maximum dose: 600mg per day.

2. Neuropathic Pain:

   • Starting dose: 150mg per day, divided into 2 or 3 doses.

   • Maintenance dose: 300mg to 600mg per day, divided into 2 or 3 doses.

   • The dosage should be adjusted based on the patient's response and tolerability.

3. Generalized Anxiety Disorder (GAD):

   • Starting dose: 150mg per day, divided into 2 or 3 doses.

   • Maintenance dose: 300mg to 600mg per day, divided into 2 or 3 doses.

   • Adjust the dose based on individual needs.

4. Fibromyalgia:

   • Starting dose: 150mg per day, divided into 2 or 3 doses.

   • Maintenance dose: 300mg to 450mg per day, divided into 2 or 3 doses.

5. Restless Legs Syndrome (RLS):

   • Starting dose: 150mg per day, divided into 2 or 3 doses.

   • Maintenance dose: 300mg per day, divided into 2 doses, adjusted based on individual needs.

Administration:

• Pregabalin (Convult) should be taken orally, with or without food.

• Capsules should be swallowed whole with a glass of water.

Side Effects:

Like all medications, Pregabalin (Convult) may cause side effects. Common side effects include:

1. Common Side Effects:

   • Dizziness or lightheadedness, especially when standing up (orthostatic hypotension).

   • Somnolence (drowsiness or tiredness).

   • Peripheral edema (swelling of the hands, feet, or ankles).

   • Weight gain.

   • Blurred vision.

   • Dry mouth.

   • Difficulty concentrating.

2. Serious Side Effects:

   • Angioedema: Swelling of the face, lips, throat, or tongue (rare, but requires immediate medical attention).

   • Suicidal thoughts or behavior: Some patients may experience depression, anxiety, or thoughts of self-harm.

   • Severe allergic reactions: Rash, itching, or difficulty breathing.

   • Muscle pain, tenderness, or weakness (may indicate rhabdomyolysis, a severe condition that can damage the muscles).

   • Vision changes: Including double vision or blurred vision.

3. Other Possible Side Effects:

   • Constipation.

   • Increased appetite.

   • Difficulty speaking or slurred speech.

   • Uncoordinated movement or difficulty with walking.

Contraindications:

Pregabalin (Convult) should not be used in the following situations:

1. Hypersensitivity:

   • Pregabalin is contraindicated in patients who have a known hypersensitivity (allergy) to pregabalin or any of the components of the formulation.

2. Severe Renal Impairment:

   • Pregabalin should be used with caution in patients with severe renal impairment, as it is primarily excreted by the kidneys. Dosing adjustments may be necessary for patients with impaired kidney function.

3. Pregnancy:

   • Pregabalin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is classified as Category C by the FDA. Pregnant women should consult their healthcare provider before taking this medication.

4. Breastfeeding:

   • Pregabalin is excreted in breast milk, so caution is recommended if this medication is prescribed to breastfeeding mothers. The benefits and risks should be weighed carefully.

5. Children under 18 years:

   • The safety and efficacy of Pregabalin in children under 18 years of age have not been established, so it is typically not recommended for use in pediatric patients unless prescribed by a specialist.

Precautions:

While using Pregabalin (Convult), consider the following precautions:

1. Suicidal Thoughts and Behavior:

   • Like many anti-epileptic drugs, pregabalin may increase the risk of suicidal thoughts or behaviors. Patients should be monitored for new or worsening symptoms of depression, anxiety, or changes in mood or behavior.

2. CNS Effects:

   • Pregabalin may cause dizziness, somnolence, and other central nervous system (CNS) effects. Caution should be exercised when driving or operating machinery, particularly when starting treatment or adjusting the dose.

3. Drug Dependence and Abuse:

   • There is some potential for abuse and dependence with pregabalin, particularly in individuals with a history of drug or alcohol abuse. It should be used with caution in these individuals.

4. Renal Impairment:

   • In patients with renal impairment, the dosage of pregabalin may need to be reduced, as the drug is primarily eliminated through the kidneys.

5. Discontinuation:

   • Pregabalin should not be abruptly discontinued, especially in patients taking it for epilepsy or neuropathic pain. Gradual tapering of the dose is recommended to reduce the risk of withdrawal symptoms or seizure exacerbation.

6. Pregnancy and Breastfeeding:

   • As mentioned earlier, pregabalin should only be used in pregnancy if necessary and prescribed by a healthcare provider. Similarly, its use during breastfeeding should be carefully considered, as the drug is excreted in breast milk.

Summary:

Pregabalin (Convult) 75mg is an anti-epileptic drug used to treat conditions like epilepsy, neuropathic pain, generalized anxiety disorder, and fibromyalgia. It works by stabilizing nerve activity and reducing symptoms related to these conditions.

The typical dosage ranges from 150mg to 600mg per day, divided into 2 or 3 doses, depending on the condition being treated. Common side effects include dizziness, somnolence, and edema, while more serious effects can include suicidal thoughts and severe allergic reactions.

Contraindications include hypersensitivity to pregabalin, severe renal impairment, and pregnancy unless absolutely necessary. It should be used with caution in patients with renal impairment, those with a history of drug abuse, and pregnant or breastfeeding women.

Pregabalin should be used under the guidance of a healthcare provider to ensure safe and effective management of the conditions for which it is prescribed.